Matches in SemOpenAlex for { <https://semopenalex.org/work/W1536096303> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W1536096303 endingPage "565" @default.
- W1536096303 startingPage "553" @default.
- W1536096303 abstract "The synthesis and properties of 3-ketodihydrosphingosine-3-14C(VIII) are described. Cell-free particulate fractions from the yeast Hansenula ciferri convert VIII exclusively to dihydrosphingosine; no 3-ketosphingosine or sphingosine could be detected. Similar fractions convert, 14C-ammonium palmitate to trams-2-hexadecenoic acid indicating that, in yeast, the biosynthetic pathways of saturated and unsaturated sphingolipids diverge at the fatty acyl CoA level. Substrate preferences for the enzyme(s) which mediates the condensation of serine with fatty acyl CoA to produce ketosphingolipid bases are: palmityl CoA > stearyl CoA > myristyl CoA > decanoyl CoA > lauryl CoA. Under appropriate conditions trans-2-hexadecenoyl CoA is an excellent substrate and, like palmityl CoA, leads to a mixture of sphingosine and dihydrosphingosine. α-Hydroxypalmityl CoA is not a substrate for the condensing enzyme and appears, therefore, not to be a precursor of phytosphingosine in yeast preparations. Most of the fatty acyl CoA derivatives tested are potent inhibitors of the condensing enzyme; bovine serum albumin is effective in reducing this inhibition." @default.
- W1536096303 created "2016-06-24" @default.
- W1536096303 creator A5020771608 @default.
- W1536096303 creator A5077567333 @default.
- W1536096303 creator A5080809708 @default.
- W1536096303 date "1971-04-01" @default.
- W1536096303 modified "2023-09-25" @default.
- W1536096303 title "Biosynthesis of sphingolipid bases" @default.
- W1536096303 cites W133701479 @default.
- W1536096303 cites W1485592454 @default.
- W1536096303 cites W1496631184 @default.
- W1536096303 cites W1498215943 @default.
- W1536096303 cites W1589926992 @default.
- W1536096303 cites W1597439947 @default.
- W1536096303 cites W1601329007 @default.
- W1536096303 cites W172241187 @default.
- W1536096303 cites W1862213828 @default.
- W1536096303 cites W1964054956 @default.
- W1536096303 cites W2015358543 @default.
- W1536096303 cites W2015793360 @default.
- W1536096303 cites W2024049489 @default.
- W1536096303 cites W2031885827 @default.
- W1536096303 cites W2052112325 @default.
- W1536096303 cites W2052310104 @default.
- W1536096303 cites W2067170260 @default.
- W1536096303 cites W2091620108 @default.
- W1536096303 cites W2100878049 @default.
- W1536096303 cites W2313767327 @default.
- W1536096303 cites W2316475291 @default.
- W1536096303 cites W2316683623 @default.
- W1536096303 cites W2316852568 @default.
- W1536096303 cites W2319777646 @default.
- W1536096303 cites W2414790722 @default.
- W1536096303 cites W2993395232 @default.
- W1536096303 cites W2993773955 @default.
- W1536096303 cites W93678597 @default.
- W1536096303 doi "https://doi.org/10.1016/0003-9861(71)90240-2" @default.
- W1536096303 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4397676" @default.
- W1536096303 hasPublicationYear "1971" @default.
- W1536096303 type Work @default.
- W1536096303 sameAs 1536096303 @default.
- W1536096303 citedByCount "42" @default.
- W1536096303 countsByYear W15360963032017 @default.
- W1536096303 countsByYear W15360963032018 @default.
- W1536096303 countsByYear W15360963032021 @default.
- W1536096303 crossrefType "journal-article" @default.
- W1536096303 hasAuthorship W1536096303A5020771608 @default.
- W1536096303 hasAuthorship W1536096303A5077567333 @default.
- W1536096303 hasAuthorship W1536096303A5080809708 @default.
- W1536096303 hasConcept C170493617 @default.
- W1536096303 hasConcept C181199279 @default.
- W1536096303 hasConcept C185592680 @default.
- W1536096303 hasConcept C18903297 @default.
- W1536096303 hasConcept C2777289219 @default.
- W1536096303 hasConcept C2778703144 @default.
- W1536096303 hasConcept C2779222958 @default.
- W1536096303 hasConcept C2779685201 @default.
- W1536096303 hasConcept C543025807 @default.
- W1536096303 hasConcept C553450214 @default.
- W1536096303 hasConcept C55493867 @default.
- W1536096303 hasConcept C61705674 @default.
- W1536096303 hasConcept C86803240 @default.
- W1536096303 hasConcept C86807702 @default.
- W1536096303 hasConceptScore W1536096303C170493617 @default.
- W1536096303 hasConceptScore W1536096303C181199279 @default.
- W1536096303 hasConceptScore W1536096303C185592680 @default.
- W1536096303 hasConceptScore W1536096303C18903297 @default.
- W1536096303 hasConceptScore W1536096303C2777289219 @default.
- W1536096303 hasConceptScore W1536096303C2778703144 @default.
- W1536096303 hasConceptScore W1536096303C2779222958 @default.
- W1536096303 hasConceptScore W1536096303C2779685201 @default.
- W1536096303 hasConceptScore W1536096303C543025807 @default.
- W1536096303 hasConceptScore W1536096303C553450214 @default.
- W1536096303 hasConceptScore W1536096303C55493867 @default.
- W1536096303 hasConceptScore W1536096303C61705674 @default.
- W1536096303 hasConceptScore W1536096303C86803240 @default.
- W1536096303 hasConceptScore W1536096303C86807702 @default.
- W1536096303 hasIssue "2" @default.
- W1536096303 hasLocation W15360963031 @default.
- W1536096303 hasLocation W15360963032 @default.
- W1536096303 hasOpenAccess W1536096303 @default.
- W1536096303 hasPrimaryLocation W15360963031 @default.
- W1536096303 hasRelatedWork W1536096303 @default.
- W1536096303 hasRelatedWork W1539477594 @default.
- W1536096303 hasRelatedWork W1982923872 @default.
- W1536096303 hasRelatedWork W2025402148 @default.
- W1536096303 hasRelatedWork W2029226682 @default.
- W1536096303 hasRelatedWork W2085982495 @default.
- W1536096303 hasRelatedWork W2157073142 @default.
- W1536096303 hasRelatedWork W4239845284 @default.
- W1536096303 hasRelatedWork W4299716051 @default.
- W1536096303 hasRelatedWork W1964299504 @default.
- W1536096303 hasVolume "143" @default.
- W1536096303 isParatext "false" @default.
- W1536096303 isRetracted "false" @default.
- W1536096303 magId "1536096303" @default.
- W1536096303 workType "article" @default.