FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1536234908> ?p ?o ?g. }

• W1536234908 abstract "While itching and scratching are important factors in the development of atopic dermatitis (AD), the mechanisms that underlie these phenomena are poorly understood. Cohousing with skin-lesioned NC/Nga mice, an animal model of AD, gradually increased itch-associated scratching behavior (LLS) counts in several strains mice. On the other hands, repeated dose of interleukin-31 (IL-31) gradually increased LLS counts due to increasing of dorsal root ganglia (DRG) IL-31 receptor A (IL-31RA) expression in mice.We investigated the relationship between the LLS counts and the expression of IL-31 and IL-31RA mRNA in the skin and DRG in mice. The LLS counts were significantly increased in NC/Nga and BALB/c mice after 3, 7 and 14 days cohoused with skin-lesioned NC/Nga mice, in a duration-dependent manner. Cohousing with skin-lesioned NC/Nga mice significantly increased the expression of mRNA for cutaneous IL-31 and DRG IL-31RA compared with these levels in non-cohoused NC/Nga and BALB/c mice, while DRG IL-31 mRNA was not observed. Increased LLS counts were closely correlated with increased DRG IL-31RA mRNA expression, but not with cutaneous IL-31 mRNA, in NC/Nga and BALB/c mice. Moreover, these phenomena were also observed in W/W v and Scid mice after 2 weeks of cohousing with skin-lesioned NC/Nga mice. DRG IL-31RA expression of CNV-NC/Nga mice were significant higher than those of SPF-NC/Nga mice. A single dose of IL-31 significantly increased LLS counts more clearly in CNV-NS/Nga than SPF-NC/Nga mice. These results suggest that IL-31-induced LLS is enhanced by DRG IL-31RA expression in mice, and cohoused induced itching is regulated by DRG IL-31RA expression as in the case of itching induced by repeated administration of IL-31." @default.
• W1536234908 created "2016-06-24" @default.
• W1536234908 creator A5000740478 @default.
• W1536234908 creator A5013380810 @default.
• W1536234908 creator A5025103209 @default.
• W1536234908 creator A5042758321 @default.
• W1536234908 creator A5052928911 @default.
• W1536234908 creator A5066264659 @default.
• W1536234908 date "2015-03-26" @default.
• W1536234908 modified "2023-09-24" @default.
• W1536234908 title "Increased itching sensation depends on an increase in the dorsal root ganglia IL-31 receptor A (IL-31RA) expression in mice with atopic-like dermatitis" @default.
• W1536234908 cites W1913271521 @default.
• W1536234908 cites W1941136997 @default.
• W1536234908 cites W1975316500 @default.
• W1536234908 cites W1977844111 @default.
• W1536234908 cites W1980331248 @default.
• W1536234908 cites W1983871703 @default.
• W1536234908 cites W1985146550 @default.
• W1536234908 cites W2002010381 @default.
• W1536234908 cites W2011737452 @default.
• W1536234908 cites W2012566509 @default.
• W1536234908 cites W2020903065 @default.
• W1536234908 cites W2025616494 @default.
• W1536234908 cites W2031056551 @default.
• W1536234908 cites W2032062642 @default.
• W1536234908 cites W2035183016 @default.
• W1536234908 cites W2045767946 @default.
• W1536234908 cites W2055718153 @default.
• W1536234908 cites W2073972348 @default.
• W1536234908 cites W2077529892 @default.
• W1536234908 cites W2083380164 @default.
• W1536234908 cites W2087384773 @default.
• W1536234908 cites W2095224028 @default.
• W1536234908 cites W2106783969 @default.
• W1536234908 cites W2119120508 @default.
• W1536234908 cites W2121696462 @default.
• W1536234908 cites W2129870718 @default.
• W1536234908 cites W2137722996 @default.
• W1536234908 cites W2317492969 @default.
• W1536234908 doi "https://doi.org/10.14800/ip.467" @default.
• W1536234908 hasPublicationYear "2015" @default.
• W1536234908 type Work @default.
• W1536234908 sameAs 1536234908 @default.
• W1536234908 citedByCount "2" @default.
• W1536234908 countsByYear W15362349082015 @default.
• W1536234908 countsByYear W15362349082016 @default.
• W1536234908 crossrefType "journal-article" @default.
• W1536234908 hasAuthorship W1536234908A5000740478 @default.
• W1536234908 hasAuthorship W1536234908A5013380810 @default.
• W1536234908 hasAuthorship W1536234908A5025103209 @default.
• W1536234908 hasAuthorship W1536234908A5042758321 @default.
• W1536234908 hasAuthorship W1536234908A5052928911 @default.
• W1536234908 hasAuthorship W1536234908A5066264659 @default.
• W1536234908 hasConcept C104317684 @default.
• W1536234908 hasConcept C105580179 @default.
• W1536234908 hasConcept C105702510 @default.
• W1536234908 hasConcept C121332964 @default.
• W1536234908 hasConcept C126322002 @default.
• W1536234908 hasConcept C134018914 @default.
• W1536234908 hasConcept C140530291 @default.
• W1536234908 hasConcept C170493617 @default.
• W1536234908 hasConcept C203014093 @default.
• W1536234908 hasConcept C24890656 @default.
• W1536234908 hasConcept C2778329239 @default.
• W1536234908 hasConcept C2779923671 @default.
• W1536234908 hasConcept C2780196728 @default.
• W1536234908 hasConcept C55493867 @default.
• W1536234908 hasConcept C71924100 @default.
• W1536234908 hasConcept C86803240 @default.
• W1536234908 hasConceptScore W1536234908C104317684 @default.
• W1536234908 hasConceptScore W1536234908C105580179 @default.
• W1536234908 hasConceptScore W1536234908C105702510 @default.
• W1536234908 hasConceptScore W1536234908C121332964 @default.
• W1536234908 hasConceptScore W1536234908C126322002 @default.
• W1536234908 hasConceptScore W1536234908C134018914 @default.
• W1536234908 hasConceptScore W1536234908C140530291 @default.
• W1536234908 hasConceptScore W1536234908C170493617 @default.
• W1536234908 hasConceptScore W1536234908C203014093 @default.
• W1536234908 hasConceptScore W1536234908C24890656 @default.
• W1536234908 hasConceptScore W1536234908C2778329239 @default.
• W1536234908 hasConceptScore W1536234908C2779923671 @default.
• W1536234908 hasConceptScore W1536234908C2780196728 @default.
• W1536234908 hasConceptScore W1536234908C55493867 @default.
• W1536234908 hasConceptScore W1536234908C71924100 @default.
• W1536234908 hasConceptScore W1536234908C86803240 @default.
• W1536234908 hasLocation W15362349081 @default.
• W1536234908 hasOpenAccess W1536234908 @default.
• W1536234908 hasPrimaryLocation W15362349081 @default.
• W1536234908 hasRelatedWork W1495558590 @default.
• W1536234908 hasRelatedWork W1503247576 @default.
• W1536234908 hasRelatedWork W1680952474 @default.
• W1536234908 hasRelatedWork W1988702609 @default.
• W1536234908 hasRelatedWork W2005620445 @default.
• W1536234908 hasRelatedWork W2015360645 @default.
• W1536234908 hasRelatedWork W2018471573 @default.
• W1536234908 hasRelatedWork W2023119659 @default.
• W1536234908 hasRelatedWork W2044854941 @default.
• W1536234908 hasRelatedWork W2049399189 @default.
• W1536234908 hasRelatedWork W2056668709 @default.
• W1536234908 hasRelatedWork W2103229419 @default.

• next