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• W1536697035 abstract "Blood group A, B, H, Lea, Leb, and I substances, their products of periodate oxidation and Smith degradation, and disaccharides containing 3-O-substituted reducing N-acetylhexosamines were treated with base-borohydride under three defined sets of conditions. Procedures for the assay and quantitation of the possible reduced base-degradation products, including hexenetetrol(s), 3-deoxygalactitol, galactitol, reduced chromogens, N-acetylglucosaminitol, and N-acetylgalactosaminitol are described. Extensive degradation occurred by two methods. 1 m NaBH4 in 0.05 n NaOH at 50 ° cleaves the glycosidic linkage of the oligosaccharide chains from serine and threonine with reduction of the terminal-reducing N-acetylgalactosamine with minimal base degradation. The method is useful for isolation of complete reduced oligosaccharides from blood group substances; the structural implications of the free and oligosaccharide-bound N-acetylgalactosaminitol released are discussed." @default.
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• W1536697035 date "1972-01-01" @default.
• W1536697035 modified "2023-09-26" @default.
• W1536697035 title "Immunochemical studies on blood groups" @default.
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• W1536697035 doi "https://doi.org/10.1016/0003-9861(72)90145-2" @default.
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