Matches in SemOpenAlex for { <https://semopenalex.org/work/W1536820588> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W1536820588 endingPage "8282" @default.
- W1536820588 startingPage "8275" @default.
- W1536820588 abstract "Difference spectra associated with changes in pH and with binding of saccharides have been recorded for hen egg white (HEW) lysozyme, turkey egg white (TEW) lysozyme, and for the derivatives of the hen protein in which Tre-62 or Trp-108 had been oxidized specifically to oxindolealanine to give the Oxa-62 or Oxa-108-proteins. Identical pH difference spectra were obtained for HEW, TEW, and Oxa-62-lysozymes. Oxidation of Trp-108 is reflected in both the high and low pH (pH 7 versus 5 and pH 2 versus 5) difference spectra. The magnitude of the low pH difference spectrum is enhanced by binding of saccharide for HEW and Oxa-62-lysozymes but not for TEW lysozyme. The shapes and magnitudes of saccharide binding difference spectra are affected by oxidation of residues 62 or 108. These results can be interpreted in terms of the perturbations responsible for the lysozyme difference spectra. The pH 7 versus 5 difference spectrum results from perturbation by Glu-35 of Trp-108 and another tryptophan, probably Trp-63. Perturbation of Trp-108 and one or more other tryptophan residues by several carboxylate groups is responsible for the low pH difference spectra of the unliganded HEW and TEW lysozyme molecules. Perturbation of Trp-108 makes a principal contribution to the saccharide-binding difference spectrum. Perturbation of the Oxa-108 chromophore by ionization of Glu-35 or by saccharide binding produces absorbance changes in the 250 to 265 nm region." @default.
- W1536820588 created "2016-06-24" @default.
- W1536820588 creator A5005588090 @default.
- W1536820588 creator A5017639848 @default.
- W1536820588 creator A5037448510 @default.
- W1536820588 creator A5054665013 @default.
- W1536820588 creator A5060627012 @default.
- W1536820588 creator A5074555776 @default.
- W1536820588 date "1975-10-01" @default.
- W1536820588 modified "2023-09-28" @default.
- W1536820588 title "Optical properties of lysozyme. pH and saccharide binding difference spectra." @default.
- W1536820588 cites W1486875326 @default.
- W1536820588 cites W1517513610 @default.
- W1536820588 cites W1527613718 @default.
- W1536820588 cites W1538549481 @default.
- W1536820588 cites W1542485898 @default.
- W1536820588 cites W1578203661 @default.
- W1536820588 cites W1593374398 @default.
- W1536820588 cites W1929204765 @default.
- W1536820588 cites W1964332426 @default.
- W1536820588 cites W1986757477 @default.
- W1536820588 cites W1990048851 @default.
- W1536820588 cites W1993442337 @default.
- W1536820588 cites W1995139112 @default.
- W1536820588 cites W1998904865 @default.
- W1536820588 cites W2001900040 @default.
- W1536820588 cites W2017429979 @default.
- W1536820588 cites W2088789387 @default.
- W1536820588 cites W2120311983 @default.
- W1536820588 cites W2161081130 @default.
- W1536820588 cites W2313998586 @default.
- W1536820588 doi "https://doi.org/10.1016/s0021-9258(19)40847-8" @default.
- W1536820588 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/240857" @default.
- W1536820588 hasPublicationYear "1975" @default.
- W1536820588 type Work @default.
- W1536820588 sameAs 1536820588 @default.
- W1536820588 citedByCount "14" @default.
- W1536820588 countsByYear W15368205882019 @default.
- W1536820588 countsByYear W15368205882023 @default.
- W1536820588 crossrefType "journal-article" @default.
- W1536820588 hasAuthorship W1536820588A5005588090 @default.
- W1536820588 hasAuthorship W1536820588A5017639848 @default.
- W1536820588 hasAuthorship W1536820588A5037448510 @default.
- W1536820588 hasAuthorship W1536820588A5054665013 @default.
- W1536820588 hasAuthorship W1536820588A5060627012 @default.
- W1536820588 hasAuthorship W1536820588A5074555776 @default.
- W1536820588 hasBestOaLocation W15368205881 @default.
- W1536820588 hasConcept C121332964 @default.
- W1536820588 hasConcept C12554922 @default.
- W1536820588 hasConcept C1276947 @default.
- W1536820588 hasConcept C185592680 @default.
- W1536820588 hasConcept C2776966407 @default.
- W1536820588 hasConcept C2910962006 @default.
- W1536820588 hasConcept C3020018894 @default.
- W1536820588 hasConcept C4839761 @default.
- W1536820588 hasConcept C55493867 @default.
- W1536820588 hasConcept C86803240 @default.
- W1536820588 hasConceptScore W1536820588C121332964 @default.
- W1536820588 hasConceptScore W1536820588C12554922 @default.
- W1536820588 hasConceptScore W1536820588C1276947 @default.
- W1536820588 hasConceptScore W1536820588C185592680 @default.
- W1536820588 hasConceptScore W1536820588C2776966407 @default.
- W1536820588 hasConceptScore W1536820588C2910962006 @default.
- W1536820588 hasConceptScore W1536820588C3020018894 @default.
- W1536820588 hasConceptScore W1536820588C4839761 @default.
- W1536820588 hasConceptScore W1536820588C55493867 @default.
- W1536820588 hasConceptScore W1536820588C86803240 @default.
- W1536820588 hasIssue "20" @default.
- W1536820588 hasLocation W15368205881 @default.
- W1536820588 hasOpenAccess W1536820588 @default.
- W1536820588 hasPrimaryLocation W15368205881 @default.
- W1536820588 hasRelatedWork W1563418569 @default.
- W1536820588 hasRelatedWork W1566365495 @default.
- W1536820588 hasRelatedWork W1572291742 @default.
- W1536820588 hasRelatedWork W2001883985 @default.
- W1536820588 hasRelatedWork W2014442658 @default.
- W1536820588 hasRelatedWork W2047326410 @default.
- W1536820588 hasRelatedWork W2056530501 @default.
- W1536820588 hasRelatedWork W2081756687 @default.
- W1536820588 hasRelatedWork W2165525780 @default.
- W1536820588 hasRelatedWork W2175517842 @default.
- W1536820588 hasVolume "250" @default.
- W1536820588 isParatext "false" @default.
- W1536820588 isRetracted "false" @default.
- W1536820588 magId "1536820588" @default.
- W1536820588 workType "article" @default.