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• W1537042434 abstract "AIMS. To determine the cardio-metabolic risk profile and incidence of low bone mineral density inAfrican and Indian postmenopausal women attending the IALCH menopause clinic and todetermine whether there is a correlation between cardio-metabolic parameters and low bonemineral density.METHODS.A retrospective, descriptive study involving all Indian and African postmenopausal women,above the age of 40, referred to the menopause outpatient clinic at IALCH from 01 July 2009to 31 December 2010 was conducted.Data was collected from the medi-com database using a structured questionnaire.Cardio-metabolic data was analysed as continuous variables and summarized using meansand standard deviations. Bone mineral density was treated as a quantitative variable andcorrelation analysis was used to assess relationships between the variables. This was done foreach race group separately. The Students T-test was used to compare cardio-metabolicvariables between the two ethnic groups. SPSS version 18.0 was used to analyse data.RESULTS.The records of 106 women were analysed (51 African and 55 Indian). In African and Indianwomen, the prevalence of hypertension was 54.9% vs 65.5%, the prevalence of diabetes was31.4% vs 56.4%, the prevalence of dyslipidaemia was 17.6% vs 32.7% and the prevalence ofischaemic heart disease was 5.9% vs 14.9% respectively. The prevalence of low bone mineraldensity was higher in Indian women (40%) compared to African women (23.5%). The meanbody mass index (BMI) of African women was significantly higher than Indian women, (33vs 29). There were no significant differences between African and Indian postmenopausalwomen regarding their lipid profile, fasting glucose, fasting insulin and thyroid profile.The mean bone mineral density (BMD) in the hip and spine was lower in Indian womencompared to African women, however the prevalence of osteopaenia and osteoporosis, asdefined by T-scores, was not statistically significant.Statistically significant positive correlations were observed between an increasing BMI andBMD (p<0.001) and increases in weight and BMD (p<0.001). A statistically significantcorrelation were observed between serum LDL-cholesterol values and BMD (p=0.03), whereserum LDL-cholesterol values were inversely proportional to BMD. There were nosignificant correlations between BMD and the remaining cardio-metabolic variables (ie bloodpressure; waist-hip ratio; clinical stigma of dyslipidaemia; clinical stigma of insulinresistance; cholesterol; HDL; triglycerides; fasting glucose; fasting insulin and thyroidfunction).CONCLUSIONS.There is a high prevalence of cardiovascular risks and low BMD amongst the localmenopausal population, irrespective of ethnicity. African and Indian postmenopausal womenhad a high prevalence of hypertension (60%), diabetes (44%), dyslipidaemia (25%) andobesity (54%). In African women, the incidence of low BMD was 35% in the hip, 53% in theneck of femur and 55% in the lumbar spine. In Indian women, the incidence of low BMDwas 55% in the hip, 67% in…" @default.
• W1537042434 created "2016-06-24" @default.
• W1537042434 creator A5055705188 @default.
• W1537042434 date "2013-01-01" @default.
• W1537042434 modified "2023-09-26" @default.
• W1537042434 title "The cardio-metabolic profile and bone mineral density in African and Indian postmenopausal women." @default.
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