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- W1537059518 abstract "Angiogenesis is essential to restore the supply of oxygen and nutrients to the developing endometriotic lesions. The revascularization of the endometrial tissue is the result of complex interactions between the shed menstrual tissue arriving in the abdominal cavity, the subsequent inflammatory response that is elicited in the peritoneal environment, and the responses of the peritoneal lining. However, information with regard to the actual processes that occur at the interface of endometrium and peritoneum leading to vascular regeneration is limited. The aim of this chapter is to gain better insight into these processes. To this end, this chapter will recapitulate how angiogenesis and vascular growth in the normal endometrium are regulated by steroid hormones and hypoxia, and discuss the state of the art with regard to the initiation of angiogenesis and branch formation. Based on current information, vascular endothelial growth factor, together with the Ang/Tie and PDGF/SDF-1α systems are key mechanisms that control the revascularization of ectopic endometrium." @default.
- W1537059518 created "2016-06-24" @default.
- W1537059518 creator A5083069711 @default.
- W1537059518 date "2011-03-10" @default.
- W1537059518 modified "2023-10-17" @default.
- W1537059518 title "Angiogenesis and Endometriosis" @default.
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- W1537059518 doi "https://doi.org/10.1002/9781444398519.ch19" @default.
- W1537059518 hasPublicationYear "2011" @default.
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