Matches in SemOpenAlex for { <https://semopenalex.org/work/W1537161431> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W1537161431 abstract "Many compounds applied in the agrochemical, food and pharmaceutical industry contain one or more chiral centers. The enantiomers of these compounds often have different effects on their targets. To prevent unwanted side effects or environmental burden, these compounds should rather be applied in their optically pure form. In this thesis two processes for large-scale enantiomer separations have been studied based on membrane technology: direct separation using an enantioselective membrane and indirect separation in which a non-selective membrane assists an enantioselective process. For intrinsic enantioselective membranes the design criteria have been evaluated, using literature data, model calculations and experimental data. This has resulted in a categorization of these membranes into two different classes: diffusion selective membranes and sorption selective membranes. Besides intrinsic enantioselective membranes, a new stacked membrane system is developed using chiral selectors that are retained by size-selective membranes. Applying an electrical potential, selective transport of the free enantiomer will occur, thus providing separation. This separation concept is evaluated for different process conditions, showing a distinct influence of the pH. Isothermal titration calorimetry is used to compare this pH dependency of the operational selectivity and the intrinsic selector selectivity, showing no influence of the process. In the last part of this thesis a model is developed for the continuous multi-stage electrodialysis system. This model is evaluated using a 20-compartment counter-current electrodialysis stack. Model calculations have shown that using an electrodialysis stack of 250 membrane compartments allows for complete separation (99%+) for our low selective ( α =1.12) model system. In conclusion, the proposed multi-stage electrodialysis separation principle, which has the advantage of making use of chiral selectors developed for existing analytical separation methods, is suitable for low selectivity (1.1-2) separations. Therefore, it provides a viable addition for the current range of large-scale enantiomer separation processes" @default.
- W1537161431 created "2016-06-24" @default.
- W1537161431 creator A5024695243 @default.
- W1537161431 date "2002-01-01" @default.
- W1537161431 modified "2023-09-23" @default.
- W1537161431 title "Enantiomer separation using membrane systems" @default.
- W1537161431 cites W2054690699 @default.
- W1537161431 cites W2064812226 @default.
- W1537161431 hasPublicationYear "2002" @default.
- W1537161431 type Work @default.
- W1537161431 sameAs 1537161431 @default.
- W1537161431 citedByCount "0" @default.
- W1537161431 crossrefType "journal-article" @default.
- W1537161431 hasAuthorship W1537161431A5024695243 @default.
- W1537161431 hasConcept C118792377 @default.
- W1537161431 hasConcept C127413603 @default.
- W1537161431 hasConcept C146686406 @default.
- W1537161431 hasConcept C161790260 @default.
- W1537161431 hasConcept C178790620 @default.
- W1537161431 hasConcept C185592680 @default.
- W1537161431 hasConcept C21951064 @default.
- W1537161431 hasConcept C2780232233 @default.
- W1537161431 hasConcept C3128022 @default.
- W1537161431 hasConcept C41625074 @default.
- W1537161431 hasConcept C42360764 @default.
- W1537161431 hasConcept C43617362 @default.
- W1537161431 hasConcept C486523 @default.
- W1537161431 hasConcept C55493867 @default.
- W1537161431 hasConcept C94005225 @default.
- W1537161431 hasConceptScore W1537161431C118792377 @default.
- W1537161431 hasConceptScore W1537161431C127413603 @default.
- W1537161431 hasConceptScore W1537161431C146686406 @default.
- W1537161431 hasConceptScore W1537161431C161790260 @default.
- W1537161431 hasConceptScore W1537161431C178790620 @default.
- W1537161431 hasConceptScore W1537161431C185592680 @default.
- W1537161431 hasConceptScore W1537161431C21951064 @default.
- W1537161431 hasConceptScore W1537161431C2780232233 @default.
- W1537161431 hasConceptScore W1537161431C3128022 @default.
- W1537161431 hasConceptScore W1537161431C41625074 @default.
- W1537161431 hasConceptScore W1537161431C42360764 @default.
- W1537161431 hasConceptScore W1537161431C43617362 @default.
- W1537161431 hasConceptScore W1537161431C486523 @default.
- W1537161431 hasConceptScore W1537161431C55493867 @default.
- W1537161431 hasConceptScore W1537161431C94005225 @default.
- W1537161431 hasLocation W15371614311 @default.
- W1537161431 hasOpenAccess W1537161431 @default.
- W1537161431 hasPrimaryLocation W15371614311 @default.
- W1537161431 hasRelatedWork W1617433793 @default.
- W1537161431 hasRelatedWork W1967930461 @default.
- W1537161431 hasRelatedWork W1979585581 @default.
- W1537161431 hasRelatedWork W2030512295 @default.
- W1537161431 hasRelatedWork W2047222396 @default.
- W1537161431 hasRelatedWork W2054690699 @default.
- W1537161431 hasRelatedWork W2067080849 @default.
- W1537161431 hasRelatedWork W2072624711 @default.
- W1537161431 hasRelatedWork W2141596384 @default.
- W1537161431 hasRelatedWork W2151733074 @default.
- W1537161431 hasRelatedWork W2324906956 @default.
- W1537161431 hasRelatedWork W2333285467 @default.
- W1537161431 hasRelatedWork W2347273399 @default.
- W1537161431 hasRelatedWork W2364434595 @default.
- W1537161431 hasRelatedWork W2410394655 @default.
- W1537161431 hasRelatedWork W2798576757 @default.
- W1537161431 hasRelatedWork W3096507100 @default.
- W1537161431 hasRelatedWork W3153922591 @default.
- W1537161431 hasRelatedWork W3155724571 @default.
- W1537161431 hasRelatedWork W2489433952 @default.
- W1537161431 isParatext "false" @default.
- W1537161431 isRetracted "false" @default.
- W1537161431 magId "1537161431" @default.
- W1537161431 workType "article" @default.