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- W1537761458 abstract "Antiphospholipid syndrome (APS) is a common and very devastating disease. It is an autoimmune disease, which differs from most other systemic autoimmune illnesses by its propensity to develop thrombosis. APS is defined as the co-occurrence of antiphospholipid antibodies (aPL) with the characteristic clinical symptoms. The problem exists on the laboratory side of the diagnosis which is important to estimate the risk of further thrombosis or pregnancy complications. The diagnosis has to be made based on the presence of aPL, which are very complex entities. The main objective of this chapter is to review the methods of the aPL determinations and the clinical utility of their presence. The aPL pathogenic mechanism will be shortly discussed with an emphasis on the relation between thrombosis and inflammation." @default.
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- W1537761458 date "2012-04-20" @default.
- W1537761458 modified "2023-10-03" @default.
- W1537761458 title "Antiphospholipid Antibodies – Detection and Clinical Importance" @default.
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- W1537761458 doi "https://doi.org/10.5772/30530" @default.
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