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- W153776883 endingPage "322" @default.
- W153776883 startingPage "277" @default.
- W153776883 abstract "Several medicinal plants are known to act as mutagenic, cocarcinogenic, and/or carcinogenic agents. Prevention of cancer and other related diseases can be pursued by avoiding exposure to these agents. This chapter reports scientific progress in detecting mutagenic and carcinogenic plants used in African traditional medicine. Over 400 African medicinal plants were screened mainly in South Africa, Nigeria, and Tunisia, for their mutagenicity and carcinogenicity for the period of 2003–2013 by in vitro and in vivo methods. The results showed that at least 64 plant species used in African traditional medicine are potentially mutagenic/carcinogenic based on their ability to induce genetic changes. Although plants used medicinally are widely assumed to be safe, the issue of quality control may, in the interim, be addressed. This chapter aims: (i) to report African medicinal plants with mutagenic/carcinogenic effects and (ii) to highlight the advanced in the methods used to detect these mutagenic/carcinogenic plants. Most of the extracts reported in this chapter were prepared from plant species with recognized toxicity, but widely used in African traditional medicine. Such plant extracts should consequently be examined carefully for their safety perspective and caution to their use should be taken." @default.
- W153776883 created "2016-06-24" @default.
- W153776883 creator A5032365635 @default.
- W153776883 creator A5050551827 @default.
- W153776883 date "2014-01-01" @default.
- W153776883 modified "2023-10-17" @default.
- W153776883 title "Mutagenicity and Carcinogenicity of African Medicinal Plants" @default.
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