FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1538003921> ?p ?o ?g. }

• W1538003921 endingPage "57" @default.
• W1538003921 startingPage "45" @default.
• W1538003921 abstract "A patient with multiple myeloma (MM), who initially presented with a predominant IgG lambda and a minor IgD lambda paraprotein pattern, is described. After chemotherapy, levels of the IgD lambda protein increased and the IgG lambda levels decreased. The following results were obtained when serum IgD was predominant. In the bone marrow, there were three plasma cell populations: a major one containing only delta chains, a minor one containing only gamma chains, and another minor one containing both delta and gamma chains. All these plasma cell populations contained lambda chains. Stimulation of circulating mononuclear cells with pokeweed mitogen (PWM) achieved differentiation of circulating B lymphocytes into plasma cells: 30% with only cytoplasmic delta lambda chains and 10% with only cytoplasmic gamma lambda chains. These IgG-containing plasma cells showed cytoplasmic reactivity with rabbit antiserum raised against monoclonal IgD which was shown to contain specificities recognizing both delta chains and idiotypic determinants present in both serum IgD lambda and IgG lambda. Circulating B lymphocytes were 'monoclonal': almost all expressed surface delta lambda chains, and a small proportion of them expressed both delta gamma and lambda chains. High levels of IgD were detected in the supernatants of all cultures, but high concentrations of IgG were only detected in those from PWM-stimulated cultures with very low levels of IgM and IgA. These findings suggest that plasma cells producing either IgD or IgG were derived from a common B-cell clone. Double paraproteinaemia exhibiting a shift in immunoglobulin production from IgG to IgD has not been previously described." @default.
• W1538003921 created "2016-06-24" @default.
• W1538003921 creator A5022449669 @default.
• W1538003921 creator A5025894116 @default.
• W1538003921 creator A5031837957 @default.
• W1538003921 creator A5054959727 @default.
• W1538003921 creator A5082131943 @default.
• W1538003921 creator A5086556836 @default.
• W1538003921 date "1985-05-01" @default.
• W1538003921 modified "2023-10-18" @default.
• W1538003921 title "Multiple myeloma with monoclonal IgG and IgD of lambda type exhibiting, under treatment, a shift from mainly IgG to mainly IgD." @default.
• W1538003921 cites W120632982 @default.
• W1538003921 cites W1550328316 @default.
• W1538003921 cites W1556977202 @default.
• W1538003921 cites W1570803214 @default.
• W1538003921 cites W1622908154 @default.
• W1538003921 cites W179091523 @default.
• W1538003921 cites W1906316425 @default.
• W1538003921 cites W1954552441 @default.
• W1538003921 cites W1977461031 @default.
• W1538003921 cites W1981632794 @default.
• W1538003921 cites W1987744415 @default.
• W1538003921 cites W1992145764 @default.
• W1538003921 cites W1997131126 @default.
• W1538003921 cites W2002484340 @default.
• W1538003921 cites W2012333507 @default.
• W1538003921 cites W2013047880 @default.
• W1538003921 cites W2016799443 @default.
• W1538003921 cites W2016945063 @default.
• W1538003921 cites W2024455898 @default.
• W1538003921 cites W2026091879 @default.
• W1538003921 cites W2048905037 @default.
• W1538003921 cites W2055554809 @default.
• W1538003921 cites W2068493153 @default.
• W1538003921 cites W2090627508 @default.
• W1538003921 cites W2094765967 @default.
• W1538003921 cites W2112197706 @default.
• W1538003921 cites W2131653968 @default.
• W1538003921 cites W2153593191 @default.
• W1538003921 cites W2170045209 @default.
• W1538003921 cites W2396330666 @default.
• W1538003921 cites W2404548907 @default.
• W1538003921 cites W2440046596 @default.
• W1538003921 cites W2444090896 @default.
• W1538003921 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1453593" @default.
• W1538003921 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3922877" @default.
• W1538003921 hasPublicationYear "1985" @default.
• W1538003921 type Work @default.
• W1538003921 sameAs 1538003921 @default.
• W1538003921 citedByCount "9" @default.
• W1538003921 countsByYear W15380039212013 @default.
• W1538003921 countsByYear W15380039212015 @default.
• W1538003921 countsByYear W15380039212016 @default.
• W1538003921 countsByYear W15380039212019 @default.
• W1538003921 crossrefType "journal-article" @default.
• W1538003921 hasAuthorship W1538003921A5022449669 @default.
• W1538003921 hasAuthorship W1538003921A5025894116 @default.
• W1538003921 hasAuthorship W1538003921A5031837957 @default.
• W1538003921 hasAuthorship W1538003921A5054959727 @default.
• W1538003921 hasAuthorship W1538003921A5082131943 @default.
• W1538003921 hasAuthorship W1538003921A5086556836 @default.
• W1538003921 hasConcept C137061746 @default.
• W1538003921 hasConcept C153911025 @default.
• W1538003921 hasConcept C159654299 @default.
• W1538003921 hasConcept C202751555 @default.
• W1538003921 hasConcept C203014093 @default.
• W1538003921 hasConcept C2776396001 @default.
• W1538003921 hasConcept C2778453870 @default.
• W1538003921 hasConcept C2781005381 @default.
• W1538003921 hasConcept C36394416 @default.
• W1538003921 hasConcept C48010095 @default.
• W1538003921 hasConcept C552990157 @default.
• W1538003921 hasConcept C55493867 @default.
• W1538003921 hasConcept C81089528 @default.
• W1538003921 hasConcept C86803240 @default.
• W1538003921 hasConceptScore W1538003921C137061746 @default.
• W1538003921 hasConceptScore W1538003921C153911025 @default.
• W1538003921 hasConceptScore W1538003921C159654299 @default.
• W1538003921 hasConceptScore W1538003921C202751555 @default.
• W1538003921 hasConceptScore W1538003921C203014093 @default.
• W1538003921 hasConceptScore W1538003921C2776396001 @default.
• W1538003921 hasConceptScore W1538003921C2778453870 @default.
• W1538003921 hasConceptScore W1538003921C2781005381 @default.
• W1538003921 hasConceptScore W1538003921C36394416 @default.
• W1538003921 hasConceptScore W1538003921C48010095 @default.
• W1538003921 hasConceptScore W1538003921C552990157 @default.
• W1538003921 hasConceptScore W1538003921C55493867 @default.
• W1538003921 hasConceptScore W1538003921C81089528 @default.
• W1538003921 hasConceptScore W1538003921C86803240 @default.
• W1538003921 hasIssue "1" @default.
• W1538003921 hasLocation W15380039211 @default.
• W1538003921 hasOpenAccess W1538003921 @default.
• W1538003921 hasPrimaryLocation W15380039211 @default.
• W1538003921 hasRelatedWork W1538003921 @default.
• W1538003921 hasRelatedWork W1543257860 @default.
• W1538003921 hasRelatedWork W1968090134 @default.
• W1538003921 hasRelatedWork W1988955679 @default.
• W1538003921 hasRelatedWork W2009889818 @default.

• next