Matches in SemOpenAlex for { <https://semopenalex.org/work/W1538762017> ?p ?o ?g. }
- W1538762017 endingPage "1095" @default.
- W1538762017 startingPage "1088" @default.
- W1538762017 abstract "To examine the management and outcomes of patients with stage I seminoma and to relate these to overall treatment burden.A total of 764 patients with stage I seminoma underwent surveillance or adjuvant radiation therapy (RT) at a single institution. First relapse on surveillance was managed with RT alone, or with combination chemotherapy (ChT) for more extensive recurrence. Second relapse was managed with ChT. Relapse after adjuvant RT was treated with ChT. The treatment burden was measured, according to the specific treatment undertaken after orchiectomy, by defining treatment episodes as follows: surgery - one episode; one course of RT - one episode; one course of ChT - one episode.In all, 484 patients underwent surveillance and 280 received adjuvant RT. The 5- and 10-year overall survival rates were 98.6 and 97.7% for surveillance, and 97.2 and 91.4% for adjuvant RT. A total of 72 (15%) patients in the surveillance group relapsed; treatment for relapse was RT (n = 56), ChT (n = 15) and surgery (n = 1). Second relapse occurred in six patients; these patients were treated with ChT. Of the patients in the adjuvant RT group, 14 (5%) relapsed: salvage treatment was 10 - ChT (n = 10) surgery (n = 1) and further RT (n = 3). The overall treatment burden represented by number of treatment episodes per patient was 0.16 in the surveillance group and 1.05 in the adjuvant RT group.Surveillance reduces the overall treatment burden in patients with stage I seminoma and is the preferred management option. The selective use of RT at first relapse for patients on surveillance leads to a similar requirement for subsequent ChT to that for patients on adjuvant RT." @default.
- W1538762017 created "2016-06-24" @default.
- W1538762017 creator A5002629653 @default.
- W1538762017 creator A5003643368 @default.
- W1538762017 creator A5013406375 @default.
- W1538762017 creator A5017024734 @default.
- W1538762017 creator A5040161479 @default.
- W1538762017 creator A5042842956 @default.
- W1538762017 creator A5061721154 @default.
- W1538762017 creator A5067591842 @default.
- W1538762017 creator A5073327231 @default.
- W1538762017 creator A5078348186 @default.
- W1538762017 date "2013-08-13" @default.
- W1538762017 modified "2023-10-17" @default.
- W1538762017 title "Treatment burden in stage I seminoma: a comparison of surveillance and adjuvant radiation therapy" @default.
- W1538762017 cites W1520577363 @default.
- W1538762017 cites W1799562664 @default.
- W1538762017 cites W1802603760 @default.
- W1538762017 cites W1974258611 @default.
- W1538762017 cites W1975032910 @default.
- W1538762017 cites W1981989535 @default.
- W1538762017 cites W1986631450 @default.
- W1538762017 cites W1998391760 @default.
- W1538762017 cites W2009146193 @default.
- W1538762017 cites W2012475949 @default.
- W1538762017 cites W2027157040 @default.
- W1538762017 cites W2042048473 @default.
- W1538762017 cites W2047398804 @default.
- W1538762017 cites W2051090934 @default.
- W1538762017 cites W2072085089 @default.
- W1538762017 cites W2080839610 @default.
- W1538762017 cites W2082240034 @default.
- W1538762017 cites W2096408134 @default.
- W1538762017 cites W2109175854 @default.
- W1538762017 cites W2109567731 @default.
- W1538762017 cites W2120291683 @default.
- W1538762017 cites W2125013166 @default.
- W1538762017 cites W2130803751 @default.
- W1538762017 cites W2140134446 @default.
- W1538762017 cites W2140211014 @default.
- W1538762017 cites W2146770164 @default.
- W1538762017 cites W2147660097 @default.
- W1538762017 cites W2152724203 @default.
- W1538762017 cites W2158551593 @default.
- W1538762017 cites W2218229785 @default.
- W1538762017 cites W2319995847 @default.
- W1538762017 cites W2438335613 @default.
- W1538762017 doi "https://doi.org/10.1111/bju.12330" @default.
- W1538762017 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23937685" @default.
- W1538762017 hasPublicationYear "2013" @default.
- W1538762017 type Work @default.
- W1538762017 sameAs 1538762017 @default.
- W1538762017 citedByCount "40" @default.
- W1538762017 countsByYear W15387620172013 @default.
- W1538762017 countsByYear W15387620172014 @default.
- W1538762017 countsByYear W15387620172015 @default.
- W1538762017 countsByYear W15387620172016 @default.
- W1538762017 countsByYear W15387620172017 @default.
- W1538762017 countsByYear W15387620172018 @default.
- W1538762017 countsByYear W15387620172019 @default.
- W1538762017 countsByYear W15387620172020 @default.
- W1538762017 countsByYear W15387620172021 @default.
- W1538762017 countsByYear W15387620172022 @default.
- W1538762017 countsByYear W15387620172023 @default.
- W1538762017 crossrefType "journal-article" @default.
- W1538762017 hasAuthorship W1538762017A5002629653 @default.
- W1538762017 hasAuthorship W1538762017A5003643368 @default.
- W1538762017 hasAuthorship W1538762017A5013406375 @default.
- W1538762017 hasAuthorship W1538762017A5017024734 @default.
- W1538762017 hasAuthorship W1538762017A5040161479 @default.
- W1538762017 hasAuthorship W1538762017A5042842956 @default.
- W1538762017 hasAuthorship W1538762017A5061721154 @default.
- W1538762017 hasAuthorship W1538762017A5067591842 @default.
- W1538762017 hasAuthorship W1538762017A5073327231 @default.
- W1538762017 hasAuthorship W1538762017A5078348186 @default.
- W1538762017 hasBestOaLocation W15387620171 @default.
- W1538762017 hasConcept C126322002 @default.
- W1538762017 hasConcept C141071460 @default.
- W1538762017 hasConcept C146357865 @default.
- W1538762017 hasConcept C151730666 @default.
- W1538762017 hasConcept C2776694085 @default.
- W1538762017 hasConcept C2777863537 @default.
- W1538762017 hasConcept C2777982462 @default.
- W1538762017 hasConcept C2778074268 @default.
- W1538762017 hasConcept C509974204 @default.
- W1538762017 hasConcept C71924100 @default.
- W1538762017 hasConcept C86803240 @default.
- W1538762017 hasConceptScore W1538762017C126322002 @default.
- W1538762017 hasConceptScore W1538762017C141071460 @default.
- W1538762017 hasConceptScore W1538762017C146357865 @default.
- W1538762017 hasConceptScore W1538762017C151730666 @default.
- W1538762017 hasConceptScore W1538762017C2776694085 @default.
- W1538762017 hasConceptScore W1538762017C2777863537 @default.
- W1538762017 hasConceptScore W1538762017C2777982462 @default.
- W1538762017 hasConceptScore W1538762017C2778074268 @default.
- W1538762017 hasConceptScore W1538762017C509974204 @default.
- W1538762017 hasConceptScore W1538762017C71924100 @default.
- W1538762017 hasConceptScore W1538762017C86803240 @default.