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- W1538765089 abstract "The aim of this study was to evaluate clinical and histopathological aspects of topical application of almescar ( Protium heptaphyllum (Aubl.) Marchand) oil resin on the healing processes of experimentally induced wounds in rats ( Rattus norvegicus ). Male rats (n=16) were randomly distributed into two experimental groups: group treated with almescar oil resin at 0.5% in isotonic solution (GO, n=8) and control group (CG, n=8). The experimental lesions were treated daily for 30 days. Macroscopic and histopathological analyses were performed on days 3, 7, 14 and 21, respectively. A wound contraction of 94.77% was recorded for GO and 93.91% 21 days after the lesion. The chemical constituents identified in the essential oil were predominantly monoterpenes, α-terpinolene (32.7%), limonene (22.0%) and 3-carene (15.0%) were identified as major components. Wounds in both groups had a significant reduction in the wound area during the trial period (p <.0001). Comparing the groups in different stages of evaluation, there were significant differences on day 3 (p = 0.0268), day 7 (p = 0.0031) and day 14 (p = .0190). In conclusion, the topical application of almescar resin oil was beneficial in the healing process of experimentally induced skin wounds in rats, making it a therapeutic option in veterinary medicine." @default.
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- W1538765089 date "2015-04-12" @default.
- W1538765089 modified "2023-09-23" @default.
- W1538765089 title "Effects of topical application of essential oil from resin of almescar (Protium heptaphyllum (Aubl.) Marchand) in experimentally induced skin wounds in rats" @default.
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- W1538765089 doi "https://doi.org/10.22409/rbcv.v22i1.722" @default.
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