Matches in SemOpenAlex for { <https://semopenalex.org/work/W153876814> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W153876814 abstract "Background and Objectives: Traumatic brain injury is one of the most common causes harmful to the health of society. Several studies have been conducted on the treatment of traumatic brain injury. The protective effects of statins on neurons have been demonstrated in numerous studies. The objective of the present study is to examine the effect of simvastatin on the short-term and long-term results of consciousness in patients with brain trauma. Methods: 66 patients with traumatic brain injury with GCS in the range of 9 to 12 were enrolled. The patients were randomly assigned to the treatment with simvastatin and placebo groups. The patients were evaluated according to GCS criteria at admission, discharge and 10 days after discharge as well as GOS criteria, one month, 3 months and 6 months after discharge. Results: No significant difference was observed between two groups, regarding the mechanism of injury, type and location of the lesion and complications. The comparison of the average temperatures showed that, the average temperature of patients treated with simvastatin was significantly lower. There was no significant difference between GCS and GOS of the two groups at all times. The comparison of GCS difference between the first and tenth days showed that the increase of GCS was higher in the group treated with simvastatin. Conclusions: The effects of statins on intracerebral hemorrhage have been confirmed, but few studies have been conducted on brain trauma. The present study revealed that though simvastatin caused no significant difference in GCS and GOS, but it had no harmful effects as well. It is recommended to conduct a study with a larger sample size and isolated groups." @default.
- W153876814 created "2016-06-24" @default.
- W153876814 creator A5058523234 @default.
- W153876814 creator A5075931887 @default.
- W153876814 creator A5080225916 @default.
- W153876814 date "2012-09-12" @default.
- W153876814 modified "2023-09-24" @default.
- W153876814 title "The effect of simvastatin on patients with traumatic brain injury." @default.
- W153876814 doi "https://doi.org/10.5249/jivr.v4i3.411" @default.
- W153876814 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3571589" @default.
- W153876814 hasPublicationYear "2012" @default.
- W153876814 type Work @default.
- W153876814 sameAs 153876814 @default.
- W153876814 citedByCount "0" @default.
- W153876814 crossrefType "journal-article" @default.
- W153876814 hasAuthorship W153876814A5058523234 @default.
- W153876814 hasAuthorship W153876814A5075931887 @default.
- W153876814 hasAuthorship W153876814A5080225916 @default.
- W153876814 hasConcept C118552586 @default.
- W153876814 hasConcept C126322002 @default.
- W153876814 hasConcept C141071460 @default.
- W153876814 hasConcept C142724271 @default.
- W153876814 hasConcept C17624336 @default.
- W153876814 hasConcept C204787440 @default.
- W153876814 hasConcept C27081682 @default.
- W153876814 hasConcept C2775855016 @default.
- W153876814 hasConcept C2776329913 @default.
- W153876814 hasConcept C2777094939 @default.
- W153876814 hasConcept C2781017439 @default.
- W153876814 hasConcept C2781156865 @default.
- W153876814 hasConcept C3018023364 @default.
- W153876814 hasConcept C42219234 @default.
- W153876814 hasConcept C71924100 @default.
- W153876814 hasConceptScore W153876814C118552586 @default.
- W153876814 hasConceptScore W153876814C126322002 @default.
- W153876814 hasConceptScore W153876814C141071460 @default.
- W153876814 hasConceptScore W153876814C142724271 @default.
- W153876814 hasConceptScore W153876814C17624336 @default.
- W153876814 hasConceptScore W153876814C204787440 @default.
- W153876814 hasConceptScore W153876814C27081682 @default.
- W153876814 hasConceptScore W153876814C2775855016 @default.
- W153876814 hasConceptScore W153876814C2776329913 @default.
- W153876814 hasConceptScore W153876814C2777094939 @default.
- W153876814 hasConceptScore W153876814C2781017439 @default.
- W153876814 hasConceptScore W153876814C2781156865 @default.
- W153876814 hasConceptScore W153876814C3018023364 @default.
- W153876814 hasConceptScore W153876814C42219234 @default.
- W153876814 hasConceptScore W153876814C71924100 @default.
- W153876814 hasIssue "3" @default.
- W153876814 hasLocation W1538768141 @default.
- W153876814 hasOpenAccess W153876814 @default.
- W153876814 hasPrimaryLocation W1538768141 @default.
- W153876814 hasRelatedWork W1965927651 @default.
- W153876814 hasRelatedWork W2015847893 @default.
- W153876814 hasRelatedWork W2035912847 @default.
- W153876814 hasRelatedWork W2042059332 @default.
- W153876814 hasRelatedWork W2139944238 @default.
- W153876814 hasRelatedWork W2208556671 @default.
- W153876814 hasRelatedWork W2288653246 @default.
- W153876814 hasRelatedWork W2306092547 @default.
- W153876814 hasRelatedWork W2354197790 @default.
- W153876814 hasRelatedWork W2379897688 @default.
- W153876814 hasRelatedWork W2408916918 @default.
- W153876814 hasRelatedWork W2411499880 @default.
- W153876814 hasRelatedWork W2801824382 @default.
- W153876814 hasRelatedWork W2889292408 @default.
- W153876814 hasRelatedWork W2909539006 @default.
- W153876814 hasRelatedWork W2992009032 @default.
- W153876814 hasRelatedWork W2996941090 @default.
- W153876814 hasRelatedWork W3039104880 @default.
- W153876814 hasRelatedWork W3104940515 @default.
- W153876814 hasRelatedWork W3122990210 @default.
- W153876814 hasVolume "4" @default.
- W153876814 isParatext "false" @default.
- W153876814 isRetracted "false" @default.
- W153876814 magId "153876814" @default.
- W153876814 workType "article" @default.