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- W1538892901 abstract "To study the ability of different tissues to recover from essential fatty acid deficiency, male rats were maintained for 25 weeks with a diet containing 10% hydrogenated coconut oil and were then transferred to a diet containing 10% corn oil. The total fatty acid compositions of brain, heart and testes lipids were determined at intervals over an 81-day period. Lipids from the deficient animals were low in the linoleic-series acids and high in oleic-series acids. Feeding corn oil to the deficient animals reversed this situation. Linoleic acid was rapidly incorporated into heart lipids, the changes in arachidonic and the higher polyunsaturated acids occurring more slowly. Slightly elevated levels of eicosatrienoic persisted after the concentration of total ω6-acids had returned to normal. Changes in brain fatty acids were slow, reflecting the slow metabolic turnover of lipids in this tissue. Docosahexaenoic acid, which is relatively high in brain lipids, was independent of the initial diet or of the supplemental corn oil diet. Arachidonic acid was more readily incorporated into the testes lipids than any other acid. Docosapentaenoic acid, the major ω6-acid of the testes from control animals, remained at a constant low level for several weeks before increasing to a level greater than that of the controls at 81 days. Both tissue and fatty acid specificities were observed." @default.
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- W1538892901 date "1968-04-01" @default.
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- W1538892901 title "Recovery of Rat Tissue Lipids from Essential Fatty Acid Deficiency: Brain, heart and testes" @default.
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- W1538892901 doi "https://doi.org/10.1093/jn/94.4.469" @default.
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