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• W153904175 abstract "In experimental skin toxicology, as well as in clinical practice, considerable individual variation in the susceptibility to irritant dermatitis is noted when doses are low. Cutaneous sensitivity and hypersensitivity are not determined by a single known factor but rather is multifactorial. Previous atopic dermatitis may predispose to irritant dermatitis. Susceptibility to irritation seems to be influenced by age, race, and genetic background, whereas sex-related differences do not seem to exist. Of biophysical skin baseline features, skin-surface pH correlated with the severity of experimentally induced irritant dermatitis, but baseline trans epidermal water loss, water-holding capacity, stratum corneum turnover time, and sebum content did not." @default.
• W153904175 created "2016-06-24" @default.
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• W153904175 date "1990-01-01" @default.
• W153904175 modified "2023-10-13" @default.
• W153904175 title "Factors Predisposing to Cutaneous Irritation" @default.
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• W153904175 doi "https://doi.org/10.1016/s0733-8635(18)30514-x" @default.
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