Matches in SemOpenAlex for { <https://semopenalex.org/work/W1539143178> ?p ?o ?g. }
- W1539143178 endingPage "21237" @default.
- W1539143178 startingPage "21232" @default.
- W1539143178 abstract "A construct of the human gene for procollagen II (COL2A1) was prepared with an internal deletion of 5 kilobases that removed 12 exons coding for 291 amino acids from near the NH2 terminus of the triple helix. The construct was then used to transfect stably a human tumor cell line (HT-1080), and clones secreting internally deleted pro alpha 1(II) chain of procollagen II were isolated. The protein was purified, and the thermal stability of the triple-helical domain was assayed by brief protease digestion. The thermal stability of the internally deleted protein was the same as that of intact collagen II even though the triple helix was 39% shorter. Additionally, the thermal stability of the collagenase A fragment was the same as that of the collagenase A fragment of normal collagen II even though it was 38% shorter. Analysis of the results suggested that the thermal stabilities of large fragments of collagen II depended primarily on their contents of -Gly-Pro-Hyp-triplets corrected for length." @default.
- W1539143178 created "2016-06-24" @default.
- W1539143178 creator A5030828941 @default.
- W1539143178 creator A5061490386 @default.
- W1539143178 creator A5088607690 @default.
- W1539143178 creator A5090529638 @default.
- W1539143178 date "1993-10-01" @default.
- W1539143178 modified "2023-09-28" @default.
- W1539143178 title "Deletion of a large domain in recombinant human procollagen II does not alter the thermal stability of the triple helix." @default.
- W1539143178 cites W1544737871 @default.
- W1539143178 cites W1545459122 @default.
- W1539143178 cites W1553932848 @default.
- W1539143178 cites W1557366448 @default.
- W1539143178 cites W1600019177 @default.
- W1539143178 cites W1965615970 @default.
- W1539143178 cites W1966044020 @default.
- W1539143178 cites W1970715789 @default.
- W1539143178 cites W1993754322 @default.
- W1539143178 cites W1994764794 @default.
- W1539143178 cites W2003292237 @default.
- W1539143178 cites W2026783024 @default.
- W1539143178 cites W2028941595 @default.
- W1539143178 cites W203031249 @default.
- W1539143178 cites W2034462747 @default.
- W1539143178 cites W2036354205 @default.
- W1539143178 cites W2056522916 @default.
- W1539143178 cites W2057020648 @default.
- W1539143178 cites W2064023190 @default.
- W1539143178 cites W2086136621 @default.
- W1539143178 cites W2086981991 @default.
- W1539143178 cites W2098447041 @default.
- W1539143178 cites W2113676927 @default.
- W1539143178 cites W2145165079 @default.
- W1539143178 cites W2158400950 @default.
- W1539143178 cites W255028057 @default.
- W1539143178 cites W4244258380 @default.
- W1539143178 cites W4253318439 @default.
- W1539143178 cites W4300941906 @default.
- W1539143178 cites W4361866465 @default.
- W1539143178 doi "https://doi.org/10.1016/s0021-9258(19)36915-7" @default.
- W1539143178 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8407960" @default.
- W1539143178 hasPublicationYear "1993" @default.
- W1539143178 type Work @default.
- W1539143178 sameAs 1539143178 @default.
- W1539143178 citedByCount "34" @default.
- W1539143178 countsByYear W15391431782013 @default.
- W1539143178 countsByYear W15391431782015 @default.
- W1539143178 crossrefType "journal-article" @default.
- W1539143178 hasAuthorship W1539143178A5030828941 @default.
- W1539143178 hasAuthorship W1539143178A5061490386 @default.
- W1539143178 hasAuthorship W1539143178A5088607690 @default.
- W1539143178 hasAuthorship W1539143178A5090529638 @default.
- W1539143178 hasBestOaLocation W15391431781 @default.
- W1539143178 hasConcept C104317684 @default.
- W1539143178 hasConcept C10919887 @default.
- W1539143178 hasConcept C12554922 @default.
- W1539143178 hasConcept C134306372 @default.
- W1539143178 hasConcept C153911025 @default.
- W1539143178 hasConcept C178790620 @default.
- W1539143178 hasConcept C185592680 @default.
- W1539143178 hasConcept C18903297 @default.
- W1539143178 hasConcept C2778530040 @default.
- W1539143178 hasConcept C2779965526 @default.
- W1539143178 hasConcept C33923547 @default.
- W1539143178 hasConcept C36503486 @default.
- W1539143178 hasConcept C40767141 @default.
- W1539143178 hasConcept C55493867 @default.
- W1539143178 hasConcept C59061564 @default.
- W1539143178 hasConcept C64348721 @default.
- W1539143178 hasConcept C71240020 @default.
- W1539143178 hasConcept C86803240 @default.
- W1539143178 hasConceptScore W1539143178C104317684 @default.
- W1539143178 hasConceptScore W1539143178C10919887 @default.
- W1539143178 hasConceptScore W1539143178C12554922 @default.
- W1539143178 hasConceptScore W1539143178C134306372 @default.
- W1539143178 hasConceptScore W1539143178C153911025 @default.
- W1539143178 hasConceptScore W1539143178C178790620 @default.
- W1539143178 hasConceptScore W1539143178C185592680 @default.
- W1539143178 hasConceptScore W1539143178C18903297 @default.
- W1539143178 hasConceptScore W1539143178C2778530040 @default.
- W1539143178 hasConceptScore W1539143178C2779965526 @default.
- W1539143178 hasConceptScore W1539143178C33923547 @default.
- W1539143178 hasConceptScore W1539143178C36503486 @default.
- W1539143178 hasConceptScore W1539143178C40767141 @default.
- W1539143178 hasConceptScore W1539143178C55493867 @default.
- W1539143178 hasConceptScore W1539143178C59061564 @default.
- W1539143178 hasConceptScore W1539143178C64348721 @default.
- W1539143178 hasConceptScore W1539143178C71240020 @default.
- W1539143178 hasConceptScore W1539143178C86803240 @default.
- W1539143178 hasIssue "28" @default.
- W1539143178 hasLocation W15391431781 @default.
- W1539143178 hasOpenAccess W1539143178 @default.
- W1539143178 hasPrimaryLocation W15391431781 @default.
- W1539143178 hasRelatedWork W111638954 @default.
- W1539143178 hasRelatedWork W1781522236 @default.
- W1539143178 hasRelatedWork W1968288366 @default.
- W1539143178 hasRelatedWork W1971835799 @default.
- W1539143178 hasRelatedWork W1976313950 @default.