Matches in SemOpenAlex for { <https://semopenalex.org/work/W1539173844> ?p ?o ?g. }
- W1539173844 endingPage "57" @default.
- W1539173844 startingPage "348" @default.
- W1539173844 abstract "Regulatory T cells (Tregs) play crucial roles in both induction and maintenance of tolerance. This active immune regulation may contribute not only to the control of immune responses to self-antigens and thereby prevent autoimmune diseases, but also the control of responses to non-self molecules in adaptive immunity. Numerous experimental and clinical studies indicate that manipulating the balance between regulatory and responder T cells is an effective strategy to control immune responsiveness after transplantation.Literature search was conducted using PubMed on the related subjects. Part of the material was based on the most recent work in the authors' laboratory.We propose some new strategies to achieve transplant tolerance in rodent animals via manipulating Treg function, including using histone deacetylase (HDAC) inhibitor to regulate Foxp3 transcription and enhance Treg suppression, induction of Treg-sparing apoptosis via Nur77, and identification of the co-inhibitory molecule herpes virus entry mediator (HVEM) as an effector molecule for Treg function.Regulation of Treg function will definitely provide us very promising tools to achieve clinical tolerance in the future." @default.
- W1539173844 created "2016-06-24" @default.
- W1539173844 creator A5007564557 @default.
- W1539173844 creator A5047555474 @default.
- W1539173844 date "2007-08-01" @default.
- W1539173844 modified "2023-09-23" @default.
- W1539173844 title "Regulating regulatory T cells to achieve transplant tolerance." @default.
- W1539173844 cites W1507979065 @default.
- W1539173844 cites W1526609910 @default.
- W1539173844 cites W1867724907 @default.
- W1539173844 cites W1947892588 @default.
- W1539173844 cites W1960197119 @default.
- W1539173844 cites W1975672275 @default.
- W1539173844 cites W1975692560 @default.
- W1539173844 cites W1980655244 @default.
- W1539173844 cites W1984695968 @default.
- W1539173844 cites W1985010149 @default.
- W1539173844 cites W1992832092 @default.
- W1539173844 cites W1996465395 @default.
- W1539173844 cites W2001955144 @default.
- W1539173844 cites W2008013653 @default.
- W1539173844 cites W2020085602 @default.
- W1539173844 cites W2020927708 @default.
- W1539173844 cites W2026426963 @default.
- W1539173844 cites W2033653733 @default.
- W1539173844 cites W2037596509 @default.
- W1539173844 cites W2040222339 @default.
- W1539173844 cites W2049727448 @default.
- W1539173844 cites W2067188588 @default.
- W1539173844 cites W2070443202 @default.
- W1539173844 cites W2071861453 @default.
- W1539173844 cites W2094701037 @default.
- W1539173844 cites W2102420815 @default.
- W1539173844 cites W2104742976 @default.
- W1539173844 cites W2105533289 @default.
- W1539173844 cites W2106282377 @default.
- W1539173844 cites W2107322032 @default.
- W1539173844 cites W2109453374 @default.
- W1539173844 cites W2110252464 @default.
- W1539173844 cites W2111811086 @default.
- W1539173844 cites W2113353389 @default.
- W1539173844 cites W2115346550 @default.
- W1539173844 cites W2117002684 @default.
- W1539173844 cites W2118705059 @default.
- W1539173844 cites W2118855102 @default.
- W1539173844 cites W2122722718 @default.
- W1539173844 cites W2131633419 @default.
- W1539173844 cites W2137049683 @default.
- W1539173844 cites W2139021664 @default.
- W1539173844 cites W2142943268 @default.
- W1539173844 cites W2147132132 @default.
- W1539173844 cites W2149748445 @default.
- W1539173844 cites W2151937278 @default.
- W1539173844 cites W2154896319 @default.
- W1539173844 cites W2159669268 @default.
- W1539173844 cites W2164186285 @default.
- W1539173844 cites W2165610297 @default.
- W1539173844 cites W2168201253 @default.
- W1539173844 cites W2170363342 @default.
- W1539173844 cites W2171393176 @default.
- W1539173844 cites W2792966232 @default.
- W1539173844 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17690028" @default.
- W1539173844 hasPublicationYear "2007" @default.
- W1539173844 type Work @default.
- W1539173844 sameAs 1539173844 @default.
- W1539173844 citedByCount "6" @default.
- W1539173844 countsByYear W15391738442012 @default.
- W1539173844 countsByYear W15391738442013 @default.
- W1539173844 countsByYear W15391738442015 @default.
- W1539173844 crossrefType "journal-article" @default.
- W1539173844 hasAuthorship W1539173844A5007564557 @default.
- W1539173844 hasAuthorship W1539173844A5047555474 @default.
- W1539173844 hasConcept C104317684 @default.
- W1539173844 hasConcept C126322002 @default.
- W1539173844 hasConcept C14036430 @default.
- W1539173844 hasConcept C203014093 @default.
- W1539173844 hasConcept C2107291 @default.
- W1539173844 hasConcept C2776090121 @default.
- W1539173844 hasConcept C2777702733 @default.
- W1539173844 hasConcept C2778296632 @default.
- W1539173844 hasConcept C2779727006 @default.
- W1539173844 hasConcept C502942594 @default.
- W1539173844 hasConcept C51785407 @default.
- W1539173844 hasConcept C54355233 @default.
- W1539173844 hasConcept C64927066 @default.
- W1539173844 hasConcept C71924100 @default.
- W1539173844 hasConcept C79484868 @default.
- W1539173844 hasConcept C86339819 @default.
- W1539173844 hasConcept C86803240 @default.
- W1539173844 hasConcept C8891405 @default.
- W1539173844 hasConcept C95444343 @default.
- W1539173844 hasConceptScore W1539173844C104317684 @default.
- W1539173844 hasConceptScore W1539173844C126322002 @default.
- W1539173844 hasConceptScore W1539173844C14036430 @default.
- W1539173844 hasConceptScore W1539173844C203014093 @default.
- W1539173844 hasConceptScore W1539173844C2107291 @default.
- W1539173844 hasConceptScore W1539173844C2776090121 @default.
- W1539173844 hasConceptScore W1539173844C2777702733 @default.