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- W1539203486 abstract "The three genotypes of HRS/J strain mice, +/+, hr/+, and hr/hr, differ only with respect to the mutant locus on chromosome 14 (hr for “hairless”) or a region closely linked to it1. Homozygous hairless” (hr/hr) mice develop a severe thymic atrophy which sets in at the age of approximately 6 months, concomitant with deficient immune responses to certain antigens2. The derangement underlying the immunodeficiency of mice which carry the hr gene includes a disproportionate distribution of T-cell subpopulations: a decrease in the number of Ly-1 and a parallel increase in the number of Ly-123 cells became noticeable in hr/hr mice at the age of 3 months and in hr/+ animals between 7 to 10 months of age3." @default.
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- W1539203486 date "1982-01-01" @default.
- W1539203486 modified "2023-09-26" @default.
- W1539203486 title "Disparity between Humoral Antibody Formation and Proliferative Reactions in Lymph Nodes: C57L/J vs. Haired and Hairless HRS/J MICE" @default.
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- W1539203486 doi "https://doi.org/10.1007/978-1-4684-9066-4_112" @default.
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- W1539203486 hasPublicationYear "1982" @default.
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