Matches in SemOpenAlex for { <https://semopenalex.org/work/W1540336382> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W1540336382 endingPage "8" @default.
- W1540336382 startingPage "1" @default.
- W1540336382 abstract "The possibility of obtaining useful scintigrams of secondary lymphoid organs after infusion of syngeneic lymphocytes labelled with technetium-99m (99mTc) was explored in a rat model. Thoracic duct lymphocyte (TDL) accumulation in various organs was measured with both 99mTc and 51Cr labelled cells, the latter processed with a method that has been shown not to damage lymphocytes. 99mTc labelled TDL did not localize properly in the lymph nodes and spleen. We could not visualize lymph nodes in scintigrams, neither could we demonstrate any difference between normal and hyperplastic spleens. Our conclusion is that radiation from the 99mTc label readily influences lymphocyte migration so that useful scintigraphy in rats and other small experimental animals becomes impossible. This was supported by results from culture experiments with 99mTc labelled, radiosensitive mouse haemopoietic progenitor cells. Theoretical considerations, including the calculations of lymphocyte self-irradiation and signal/noise ratios during scintigraphy of rat tissues, supported our conclusion that scintigraphy in small animals, to disclose the physiological migration of lymphocytes, may be impossible with the present sensitivity of gamma cameras." @default.
- W1540336382 created "2016-06-24" @default.
- W1540336382 creator A5015251060 @default.
- W1540336382 creator A5017777873 @default.
- W1540336382 creator A5072822314 @default.
- W1540336382 creator A5086410043 @default.
- W1540336382 date "1990-12-01" @default.
- W1540336382 modified "2023-09-23" @default.
- W1540336382 title "Migration of 99mTc-labelled syngeneic lymphocytes in the rat" @default.
- W1540336382 cites W1562341889 @default.
- W1540336382 cites W1581108772 @default.
- W1540336382 cites W180480359 @default.
- W1540336382 cites W1816425910 @default.
- W1540336382 cites W1942232650 @default.
- W1540336382 cites W1971106345 @default.
- W1540336382 cites W1978620074 @default.
- W1540336382 cites W1984701843 @default.
- W1540336382 cites W1996254349 @default.
- W1540336382 cites W2009604637 @default.
- W1540336382 cites W2013257561 @default.
- W1540336382 cites W2022558035 @default.
- W1540336382 cites W2024051143 @default.
- W1540336382 cites W2041802863 @default.
- W1540336382 cites W2055969060 @default.
- W1540336382 cites W2069050679 @default.
- W1540336382 cites W2074359987 @default.
- W1540336382 cites W2075112937 @default.
- W1540336382 cites W2075681696 @default.
- W1540336382 cites W2090582620 @default.
- W1540336382 cites W2128360206 @default.
- W1540336382 cites W2158709967 @default.
- W1540336382 cites W2401772844 @default.
- W1540336382 cites W2403811268 @default.
- W1540336382 doi "https://doi.org/10.1016/0022-1759(90)90249-u" @default.
- W1540336382 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2273251" @default.
- W1540336382 hasPublicationYear "1990" @default.
- W1540336382 type Work @default.
- W1540336382 sameAs 1540336382 @default.
- W1540336382 citedByCount "3" @default.
- W1540336382 crossrefType "journal-article" @default.
- W1540336382 hasAuthorship W1540336382A5015251060 @default.
- W1540336382 hasAuthorship W1540336382A5017777873 @default.
- W1540336382 hasAuthorship W1540336382A5072822314 @default.
- W1540336382 hasAuthorship W1540336382A5086410043 @default.
- W1540336382 hasConcept C142724271 @default.
- W1540336382 hasConcept C181152851 @default.
- W1540336382 hasConcept C185592680 @default.
- W1540336382 hasConcept C203014093 @default.
- W1540336382 hasConcept C2777593132 @default.
- W1540336382 hasConcept C2777761686 @default.
- W1540336382 hasConcept C2779720271 @default.
- W1540336382 hasConcept C2779902710 @default.
- W1540336382 hasConcept C2780931953 @default.
- W1540336382 hasConcept C2989005 @default.
- W1540336382 hasConcept C4375535 @default.
- W1540336382 hasConcept C522557706 @default.
- W1540336382 hasConcept C71924100 @default.
- W1540336382 hasConcept C86803240 @default.
- W1540336382 hasConceptScore W1540336382C142724271 @default.
- W1540336382 hasConceptScore W1540336382C181152851 @default.
- W1540336382 hasConceptScore W1540336382C185592680 @default.
- W1540336382 hasConceptScore W1540336382C203014093 @default.
- W1540336382 hasConceptScore W1540336382C2777593132 @default.
- W1540336382 hasConceptScore W1540336382C2777761686 @default.
- W1540336382 hasConceptScore W1540336382C2779720271 @default.
- W1540336382 hasConceptScore W1540336382C2779902710 @default.
- W1540336382 hasConceptScore W1540336382C2780931953 @default.
- W1540336382 hasConceptScore W1540336382C2989005 @default.
- W1540336382 hasConceptScore W1540336382C4375535 @default.
- W1540336382 hasConceptScore W1540336382C522557706 @default.
- W1540336382 hasConceptScore W1540336382C71924100 @default.
- W1540336382 hasConceptScore W1540336382C86803240 @default.
- W1540336382 hasIssue "1-2" @default.
- W1540336382 hasLocation W15403363821 @default.
- W1540336382 hasLocation W15403363822 @default.
- W1540336382 hasOpenAccess W1540336382 @default.
- W1540336382 hasPrimaryLocation W15403363821 @default.
- W1540336382 hasRelatedWork W1044780602 @default.
- W1540336382 hasRelatedWork W132628744 @default.
- W1540336382 hasRelatedWork W1544987284 @default.
- W1540336382 hasRelatedWork W1986383373 @default.
- W1540336382 hasRelatedWork W2021837844 @default.
- W1540336382 hasRelatedWork W2077898287 @default.
- W1540336382 hasRelatedWork W2107486514 @default.
- W1540336382 hasRelatedWork W4251105818 @default.
- W1540336382 hasRelatedWork W4313310228 @default.
- W1540336382 hasRelatedWork W104245943 @default.
- W1540336382 hasVolume "135" @default.
- W1540336382 isParatext "false" @default.
- W1540336382 isRetracted "false" @default.
- W1540336382 magId "1540336382" @default.
- W1540336382 workType "article" @default.