FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1540386974> ?p ?o ?g. }

• W1540386974 endingPage "437" @default.
• W1540386974 startingPage "413" @default.
• W1540386974 abstract "Linkage disequilibrium mapping attempts to infer the location of a disease gene from observed associations between marker alleles and disease phenotype. This approach can be quite powerful when disease chromosomes are descended from a single founder mutation and the markers considered are tightly linked to the disease locus. The success of linkage disequilibrium map ping in fine-scale localization has led to the suggestion that genome-wide association testing might be useful in the detection of susceptibility genes for complex traits. Such studies would likely be performed in small, relatively isolated founder populations, where heterogeneity of the disease is less likely. To interpret the patterns of association observed in such populations, we need to understand the effect of population size, history, and structure on linkage disequilibrium. In this chapter, we first review measures of allelic association at a single locus. Measures of association between two loci are described, and some theoretical results are reviewed. We then consider some methods for inferring linkage between a marker and a rare disease, focusing on those that model the ancestry of the disease chromosomes. Next we discuss factors whose effect on disequilibrium are understood, and finally we describe the characteristics of some human populations that may be useful for disequilibrium mapping of complex traits." @default.
• W1540386974 created "2016-06-24" @default.
• W1540386974 creator A5017478622 @default.
• W1540386974 creator A5086436790 @default.
• W1540386974 date "2001-01-01" @default.
• W1540386974 modified "2023-09-25" @default.
• W1540386974 title "25 Linkage disequilibrium mapping: The role of population history, size, and structure" @default.
• W1540386974 cites W1776672211 @default.
• W1540386974 cites W1963697125 @default.
• W1540386974 cites W1964737931 @default.
• W1540386974 cites W1981169569 @default.
• W1540386974 cites W1982232514 @default.
• W1540386974 cites W1984046516 @default.
• W1540386974 cites W1986674407 @default.
• W1540386974 cites W2005509217 @default.
• W1540386974 cites W2006712471 @default.
• W1540386974 cites W2009110510 @default.
• W1540386974 cites W2009171533 @default.
• W1540386974 cites W2011258019 @default.
• W1540386974 cites W2013574847 @default.
• W1540386974 cites W2017154320 @default.
• W1540386974 cites W2022177992 @default.
• W1540386974 cites W2022322532 @default.
• W1540386974 cites W2022927772 @default.
• W1540386974 cites W2040680124 @default.
• W1540386974 cites W2042103448 @default.
• W1540386974 cites W2076127299 @default.
• W1540386974 cites W2087163396 @default.
• W1540386974 cites W2124277514 @default.
• W1540386974 cites W2124288583 @default.
• W1540386974 cites W2124806507 @default.
• W1540386974 cites W2129884189 @default.
• W1540386974 cites W2134955391 @default.
• W1540386974 cites W2153039235 @default.
• W1540386974 cites W2159103438 @default.
• W1540386974 cites W2169179874 @default.
• W1540386974 cites W2208088588 @default.
• W1540386974 cites W4210633230 @default.
• W1540386974 cites W4232591682 @default.
• W1540386974 doi "https://doi.org/10.1016/s0065-2660(01)42034-7" @default.
• W1540386974 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11037333" @default.
• W1540386974 hasPublicationYear "2001" @default.
• W1540386974 type Work @default.
• W1540386974 sameAs 1540386974 @default.
• W1540386974 citedByCount "66" @default.
• W1540386974 countsByYear W15403869742012 @default.
• W1540386974 countsByYear W15403869742013 @default.
• W1540386974 countsByYear W15403869742014 @default.
• W1540386974 countsByYear W15403869742015 @default.
• W1540386974 countsByYear W15403869742016 @default.
• W1540386974 countsByYear W15403869742019 @default.
• W1540386974 countsByYear W15403869742020 @default.
• W1540386974 countsByYear W15403869742021 @default.
• W1540386974 countsByYear W15403869742023 @default.
• W1540386974 crossrefType "book-chapter" @default.
• W1540386974 hasAuthorship W1540386974A5017478622 @default.
• W1540386974 hasAuthorship W1540386974A5086436790 @default.
• W1540386974 hasConcept C104317684 @default.
• W1540386974 hasConcept C118487528 @default.
• W1540386974 hasConcept C134443026 @default.
• W1540386974 hasConcept C135763542 @default.
• W1540386974 hasConcept C144024400 @default.
• W1540386974 hasConcept C149923435 @default.
• W1540386974 hasConcept C153209595 @default.
• W1540386974 hasConcept C180754005 @default.
• W1540386974 hasConcept C186413461 @default.
• W1540386974 hasConcept C197754878 @default.
• W1540386974 hasConcept C2778146401 @default.
• W1540386974 hasConcept C2908647359 @default.
• W1540386974 hasConcept C35605836 @default.
• W1540386974 hasConcept C54355233 @default.
• W1540386974 hasConcept C71924100 @default.
• W1540386974 hasConcept C78458016 @default.
• W1540386974 hasConcept C84597430 @default.
• W1540386974 hasConcept C86803240 @default.
• W1540386974 hasConcept C97603047 @default.
• W1540386974 hasConceptScore W1540386974C104317684 @default.
• W1540386974 hasConceptScore W1540386974C118487528 @default.
• W1540386974 hasConceptScore W1540386974C134443026 @default.
• W1540386974 hasConceptScore W1540386974C135763542 @default.
• W1540386974 hasConceptScore W1540386974C144024400 @default.
• W1540386974 hasConceptScore W1540386974C149923435 @default.
• W1540386974 hasConceptScore W1540386974C153209595 @default.
• W1540386974 hasConceptScore W1540386974C180754005 @default.
• W1540386974 hasConceptScore W1540386974C186413461 @default.
• W1540386974 hasConceptScore W1540386974C197754878 @default.
• W1540386974 hasConceptScore W1540386974C2778146401 @default.
• W1540386974 hasConceptScore W1540386974C2908647359 @default.
• W1540386974 hasConceptScore W1540386974C35605836 @default.
• W1540386974 hasConceptScore W1540386974C54355233 @default.
• W1540386974 hasConceptScore W1540386974C71924100 @default.
• W1540386974 hasConceptScore W1540386974C78458016 @default.
• W1540386974 hasConceptScore W1540386974C84597430 @default.
• W1540386974 hasConceptScore W1540386974C86803240 @default.
• W1540386974 hasConceptScore W1540386974C97603047 @default.
• W1540386974 hasFunder F4320306133 @default.
• W1540386974 hasFunder F4320332161 @default.
• W1540386974 hasLocation W15403869741 @default.

• next