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- W1540391133 abstract "Abstract Rabbit antisera directed against the major structural antigens of Friend leukemia virus (FLV) were used to test a variety of mammalian cell lines in a complement-dependent cytotoxic assay. A strong reaction was obtained with proteins GP71 and P12 antisera on murine C-virus-producing cells. P12 antiserum revealed type-specific reactivity; GP71 antiserum, type- and group-specific reactivity. In addition, the latter showed a weak but reproducible interspecies reactivity, detectable with cat cells producing classical feline virus but not with two simian cell lines producing gibbon and woolly monkey C-type viruses. P10, P15, and P31 antigens acted as cytotoxic targets only on a single murine cell line producing large quantities of Friend leukemia virus, and here only to a lower degree as compared to P12 and GP71 antigens. All of the three lines of murine sarcoma virus-transformed nonproducer cells examined (K Balb, MSV85, and HT-1) were negative when reacted with the P10, P12, P15, P31, and GP71 antisera." @default.
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- W1540391133 date "1976-01-01" @default.
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- W1540391133 title "Properties of mouse leukemia viruses" @default.
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- W1540391133 doi "https://doi.org/10.1016/0042-6822(76)90203-8" @default.
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