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- W1540473357 abstract "Publisher Summary This chapter reviews that the neuropathies are the commonest long-term microvascular complication of diabetes. The clinical features of the diabetic neuropathies vary immensely, and only a minority is associated with pain. The neuropathies are characterized by a progressive loss of nerve fibers, affecting both the autonomic and somatic divisions of the nervous system. There is increasing evidence that measures of neuropathy, including quantitative tests and electrophysiology, are predictors not only of end points such as foot ulcers and even amputation, but also of mortality. The chapter discusses the pathogenesis of the diabetic neuropathies, together with the clinical features and epidemiology of those neuropathies associated with painful symptomatology. Numerous classification systems have been proposed for the variety of syndromes affecting the peripheral nervous system in diabetes. They have been based upon presumed etiology, topographical abnormalities or pathological features. The chapter also focuses on the commonest of the painful neuropathies, chronic sensorimotor diabetic neuropathy." @default.
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- W1540473357 date "2006-01-01" @default.
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- W1540473357 title "Chapter 40 Painful diabetic neuropathies" @default.
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- W1540473357 doi "https://doi.org/10.1016/s0072-9752(06)80044-8" @default.
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