Matches in SemOpenAlex for { <https://semopenalex.org/work/W1540791108> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W1540791108 endingPage "28" @default.
- W1540791108 startingPage "17" @default.
- W1540791108 abstract "We performed a systematic search for new structural motifs isohelical to double-stranded DNA and found five motifs that can be used for the design and synthesis of new DNA-binding oligomers. Some of the DNA-binding oligomers can be equipped with fluorescence chromophores and metal-chelating groups and may serve as conductive wires in nano-scaled electric circuits. A series of new DNA-binding ligands were synthesized by a modular assembly of pyrrole carboxamides and novel pseudopeptides of the form (XY)n. Here, Y is a glycine residue; n is the degree of polymerization. X is an unusual amino acid residue containing a five-membered aromatic ring. Antiviral activity of bis-linked netropsin derivatives is studied. Bis-netropsins containing 15 and 31 lysine residues at the N-termini inhibit most effectively reproduction of the herpes virus type 1 in the Vero cell culture, including virus variants resistant to acyclovir and its analogues. Antiviral activity of bis-linked netropsin derivatives is correlated with their ability to interact with long clusters of AT-base pairs in the origin of replication of the viral DNA." @default.
- W1540791108 created "2016-06-24" @default.
- W1540791108 creator A5009938411 @default.
- W1540791108 creator A5020279265 @default.
- W1540791108 creator A5030284765 @default.
- W1540791108 creator A5042614909 @default.
- W1540791108 creator A5044775475 @default.
- W1540791108 creator A5055600214 @default.
- W1540791108 date "2008-01-01" @default.
- W1540791108 modified "2023-10-16" @default.
- W1540791108 title "Isohelical DNA-Binding Oligomers: Antiviral Activity and Application for the Design of Nanostructured Devices" @default.
- W1540791108 cites W138306896 @default.
- W1540791108 cites W1658532712 @default.
- W1540791108 cites W1973500838 @default.
- W1540791108 cites W1976396183 @default.
- W1540791108 cites W1984052620 @default.
- W1540791108 cites W1986922777 @default.
- W1540791108 cites W1991282733 @default.
- W1540791108 cites W1993209440 @default.
- W1540791108 cites W2000886481 @default.
- W1540791108 cites W2000978508 @default.
- W1540791108 cites W2008125587 @default.
- W1540791108 cites W2009776141 @default.
- W1540791108 cites W2011475362 @default.
- W1540791108 cites W2018996043 @default.
- W1540791108 cites W2020937281 @default.
- W1540791108 cites W2031262928 @default.
- W1540791108 cites W2037586384 @default.
- W1540791108 cites W2037898928 @default.
- W1540791108 cites W2042267577 @default.
- W1540791108 cites W2042941607 @default.
- W1540791108 cites W2047289523 @default.
- W1540791108 cites W2055443077 @default.
- W1540791108 cites W2055487676 @default.
- W1540791108 cites W2055743289 @default.
- W1540791108 cites W2056104022 @default.
- W1540791108 cites W2060384167 @default.
- W1540791108 cites W2062077031 @default.
- W1540791108 cites W2063492068 @default.
- W1540791108 cites W2077610849 @default.
- W1540791108 cites W2082131361 @default.
- W1540791108 cites W2087976990 @default.
- W1540791108 cites W2093470415 @default.
- W1540791108 cites W2094548213 @default.
- W1540791108 cites W2104310670 @default.
- W1540791108 cites W2132451162 @default.
- W1540791108 cites W2147421370 @default.
- W1540791108 cites W2167446444 @default.
- W1540791108 cites W2300825178 @default.
- W1540791108 cites W281221377 @default.
- W1540791108 cites W62739747 @default.
- W1540791108 doi "https://doi.org/10.1007/978-1-4020-6829-4_2" @default.
- W1540791108 hasPublicationYear "2008" @default.
- W1540791108 type Work @default.
- W1540791108 sameAs 1540791108 @default.
- W1540791108 citedByCount "0" @default.
- W1540791108 crossrefType "book-chapter" @default.
- W1540791108 hasAuthorship W1540791108A5009938411 @default.
- W1540791108 hasAuthorship W1540791108A5020279265 @default.
- W1540791108 hasAuthorship W1540791108A5030284765 @default.
- W1540791108 hasAuthorship W1540791108A5042614909 @default.
- W1540791108 hasAuthorship W1540791108A5044775475 @default.
- W1540791108 hasAuthorship W1540791108A5055600214 @default.
- W1540791108 hasConcept C178790620 @default.
- W1540791108 hasConcept C185592680 @default.
- W1540791108 hasConcept C192468462 @default.
- W1540791108 hasConcept C21951064 @default.
- W1540791108 hasConcept C2781063032 @default.
- W1540791108 hasConcept C3019303373 @default.
- W1540791108 hasConcept C552990157 @default.
- W1540791108 hasConcept C55493867 @default.
- W1540791108 hasConcept C71240020 @default.
- W1540791108 hasConceptScore W1540791108C178790620 @default.
- W1540791108 hasConceptScore W1540791108C185592680 @default.
- W1540791108 hasConceptScore W1540791108C192468462 @default.
- W1540791108 hasConceptScore W1540791108C21951064 @default.
- W1540791108 hasConceptScore W1540791108C2781063032 @default.
- W1540791108 hasConceptScore W1540791108C3019303373 @default.
- W1540791108 hasConceptScore W1540791108C552990157 @default.
- W1540791108 hasConceptScore W1540791108C55493867 @default.
- W1540791108 hasConceptScore W1540791108C71240020 @default.
- W1540791108 hasLocation W15407911081 @default.
- W1540791108 hasOpenAccess W1540791108 @default.
- W1540791108 hasPrimaryLocation W15407911081 @default.
- W1540791108 hasRelatedWork W2035707154 @default.
- W1540791108 hasRelatedWork W2056382899 @default.
- W1540791108 hasRelatedWork W2056449924 @default.
- W1540791108 hasRelatedWork W2169336373 @default.
- W1540791108 hasRelatedWork W2359528737 @default.
- W1540791108 hasRelatedWork W2430171123 @default.
- W1540791108 hasRelatedWork W2431320228 @default.
- W1540791108 hasRelatedWork W1976843409 @default.
- W1540791108 hasRelatedWork W2125191912 @default.
- W1540791108 hasRelatedWork W2181976816 @default.
- W1540791108 isParatext "false" @default.
- W1540791108 isRetracted "false" @default.
- W1540791108 magId "1540791108" @default.
- W1540791108 workType "book-chapter" @default.