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- W1540974727 abstract "Bacteria are increasingly being employed as components in biosensors and biofilm reactors. It is important to understand the material properties of bacteria in dry conditions for these applications. For a decade, Atomic Force Microscopy (AFM) has been the primary tool used to study the adhesion and elastic properties of individual bacteria. In this work we show it is possible to use a Surface Forces Apparatus (SFA) to measure elastic and adhesive properties of small collections of surface bound bacteria. The measurements are conducted with submonolayer, patterned bacterial films and we have developed a protocol to image the contact area with AFM after the experiment. Using the SFA, we measured the force profile between a Pseudomonas aeruginosa PAO1 film and a bare mica surface. Pseudomonas aeruginosa PAO1 is a ubiquitous gram-negative soil bacterium and is also an opportunistic pathogen. We repeated the measurement in the same contact position for a number of days to determine the effect of desiccation on the film material properties." @default.
- W1540974727 created "2016-06-24" @default.
- W1540974727 creator A5041724950 @default.
- W1540974727 date "2008-05-30" @default.
- W1540974727 modified "2023-09-27" @default.
- W1540974727 title "Directly Measuring Adhesive and Elastic Properties of Bacteria Using a Surface Force Apparatus" @default.
- W1540974727 doi "https://doi.org/10.1021/bk-2008-0984.ch013" @default.
- W1540974727 hasPublicationYear "2008" @default.
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