FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1541410667> ?p ?o ?g. }

• W1541410667 endingPage "822" @default.
• W1541410667 startingPage "816" @default.
• W1541410667 abstract "Objective Sufficient fetal DNA in a maternal plasma sample is required for accurate aneuploidy detection via noninvasive prenatal testing, thus highlighting a need to understand the factors affecting fetal fraction. Method The MaterniT21™ PLUS test uses massively parallel sequencing to analyze cell-free fetal DNA in maternal plasma and detect chromosomal abnormalities. We assess the impact of a variety of factors, both maternal and fetal, on the fetal fraction across a large number of samples processed by Sequenom Laboratories. Results The rate of increase in fetal fraction with increasing gestational age varies across the duration of the testing period and is also influenced by fetal aneuploidy status. Maternal weight trends inversely with fetal fraction, and we find no added benefit from analyzing body mass index or blood volume instead of weight. Strong correlations exist between fetal fractions from aliquots taken from the same patient at the same blood draw and also at different blood draws. Conclusion While a number of factors trend with fetal fraction across the cohort as a whole, they are not the sole determinants of fetal fraction. In this study, the variability for any one patient does not appear large enough to justify postponing testing to a later gestational age. © 2015 John Wiley & Sons, Ltd." @default.
• W1541410667 created "2016-06-24" @default.
• W1541410667 creator A5008734746 @default.
• W1541410667 creator A5009035036 @default.
• W1541410667 creator A5009691103 @default.
• W1541410667 creator A5021263152 @default.
• W1541410667 creator A5030652794 @default.
• W1541410667 creator A5040902716 @default.
• W1541410667 creator A5042028427 @default.
• W1541410667 creator A5048785308 @default.
• W1541410667 creator A5075723539 @default.
• W1541410667 creator A5079391774 @default.
• W1541410667 date "2015-07-14" @default.
• W1541410667 modified "2023-10-10" @default.
• W1541410667 title "Factors affecting levels of circulating cell-free fetal DNA in maternal plasma and their implications for noninvasive prenatal testing" @default.
• W1541410667 cites W1517689472 @default.
• W1541410667 cites W1576120545 @default.
• W1541410667 cites W1577578665 @default.
• W1541410667 cites W1586519278 @default.
• W1541410667 cites W1607914109 @default.
• W1541410667 cites W1720911209 @default.
• W1541410667 cites W1941739197 @default.
• W1541410667 cites W1966061273 @default.
• W1541410667 cites W1984290204 @default.
• W1541410667 cites W2056785446 @default.
• W1541410667 cites W2078927009 @default.
• W1541410667 cites W2079300331 @default.
• W1541410667 cites W2100977485 @default.
• W1541410667 cites W2115865929 @default.
• W1541410667 cites W2120425005 @default.
• W1541410667 cites W2123370218 @default.
• W1541410667 cites W2129125677 @default.
• W1541410667 cites W2141302105 @default.
• W1541410667 cites W2144067971 @default.
• W1541410667 cites W2160764289 @default.
• W1541410667 cites W2164298293 @default.
• W1541410667 cites W2164422164 @default.
• W1541410667 cites W2166036749 @default.
• W1541410667 cites W2169279496 @default.
• W1541410667 cites W2172268977 @default.
• W1541410667 doi "https://doi.org/10.1002/pd.4625" @default.
• W1541410667 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26013964" @default.
• W1541410667 hasPublicationYear "2015" @default.
• W1541410667 type Work @default.
• W1541410667 sameAs 1541410667 @default.
• W1541410667 citedByCount "105" @default.
• W1541410667 countsByYear W15414106672015 @default.
• W1541410667 countsByYear W15414106672016 @default.
• W1541410667 countsByYear W15414106672017 @default.
• W1541410667 countsByYear W15414106672018 @default.
• W1541410667 countsByYear W15414106672019 @default.
• W1541410667 countsByYear W15414106672020 @default.
• W1541410667 countsByYear W15414106672021 @default.
• W1541410667 countsByYear W15414106672022 @default.
• W1541410667 countsByYear W15414106672023 @default.
• W1541410667 crossrefType "journal-article" @default.
• W1541410667 hasAuthorship W1541410667A5008734746 @default.
• W1541410667 hasAuthorship W1541410667A5009035036 @default.
• W1541410667 hasAuthorship W1541410667A5009691103 @default.
• W1541410667 hasAuthorship W1541410667A5021263152 @default.
• W1541410667 hasAuthorship W1541410667A5030652794 @default.
• W1541410667 hasAuthorship W1541410667A5040902716 @default.
• W1541410667 hasAuthorship W1541410667A5042028427 @default.
• W1541410667 hasAuthorship W1541410667A5048785308 @default.
• W1541410667 hasAuthorship W1541410667A5075723539 @default.
• W1541410667 hasAuthorship W1541410667A5079391774 @default.
• W1541410667 hasConcept C104317684 @default.
• W1541410667 hasConcept C131872663 @default.
• W1541410667 hasConcept C149629883 @default.
• W1541410667 hasConcept C152110520 @default.
• W1541410667 hasConcept C16685009 @default.
• W1541410667 hasConcept C172680121 @default.
• W1541410667 hasConcept C178790620 @default.
• W1541410667 hasConcept C185592680 @default.
• W1541410667 hasConcept C2778258057 @default.
• W1541410667 hasConcept C2778376644 @default.
• W1541410667 hasConcept C2779234561 @default.
• W1541410667 hasConcept C2779672484 @default.
• W1541410667 hasConcept C30481170 @default.
• W1541410667 hasConcept C42407357 @default.
• W1541410667 hasConcept C46973012 @default.
• W1541410667 hasConcept C54355233 @default.
• W1541410667 hasConcept C71924100 @default.
• W1541410667 hasConcept C86803240 @default.
• W1541410667 hasConceptScore W1541410667C104317684 @default.
• W1541410667 hasConceptScore W1541410667C131872663 @default.
• W1541410667 hasConceptScore W1541410667C149629883 @default.
• W1541410667 hasConceptScore W1541410667C152110520 @default.
• W1541410667 hasConceptScore W1541410667C16685009 @default.
• W1541410667 hasConceptScore W1541410667C172680121 @default.
• W1541410667 hasConceptScore W1541410667C178790620 @default.
• W1541410667 hasConceptScore W1541410667C185592680 @default.
• W1541410667 hasConceptScore W1541410667C2778258057 @default.
• W1541410667 hasConceptScore W1541410667C2778376644 @default.
• W1541410667 hasConceptScore W1541410667C2779234561 @default.
• W1541410667 hasConceptScore W1541410667C2779672484 @default.
• W1541410667 hasConceptScore W1541410667C30481170 @default.
• W1541410667 hasConceptScore W1541410667C42407357 @default.

• next