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- W1541576365 abstract "The relationship between the vitamin A activity of the yellow carotenes of plants and the colorless growth factor in liver oils became clearer after Moore demonstrated that carotene was metabolized in the animal body to form vitamin A, which was stored in the liver. The resemblance of the structure of vitamin A, elucidated by Karrer and others., to half the 8-carotene molecule suggested to them that it might be formed from the latter by central fission involving the addition of the equivalent of two molecules of water. The enzyme carotenase concerned was then sought in liver tissue where the vitamin appears in highest concentration. The experimental evidence at that time for its presence in liver yielded conflicting results, and in general the case was regarded as not proved. Although everyone agreed that β-carotene administered orally was transformed into vitamin A; great difficulty was encountered in demonstrating the conversion when the provitamin was administered parenterally." @default.
- W1541576365 created "2016-06-24" @default.
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- W1541576365 date "1961-01-01" @default.
- W1541576365 modified "2023-09-28" @default.
- W1541576365 title "The Conversion of β-Carotene into Vitamin A" @default.
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- W1541576365 doi "https://doi.org/10.1016/s0083-6729(08)60869-9" @default.
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