FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W154177512> ?p ?o ?g. }

• W154177512 endingPage "88" @default.
• W154177512 startingPage "79" @default.
• W154177512 abstract "We have tested the sera of 25 patients with systemic lupus erythematosus (SLE) for antibody activity against a panel of six antigens: DNA, TNP, actin, tubulin, myosin, albumin. Eluates from renal biopsy tissue were also tested. Sera from patients with lupus nephritis were found to contain high titres of IgA antibodies directed against the antigens of the panel, and marked IgG anti-DNA and anti-TNP antibody activity. The IgG anti-TNP antibodies isolated from SLE serum by affinity chromatography on a TNP-immunoadsorbent, were also found to possess anti-DNA activity. Kidney eluates obtained from biopsy specimens of SLE patients contained IgG antibodies strictly specific for DNA in three out of the nine patients tested, while three eluates from the remaining six patients reacted with DNA and TNP and three with DNA and all the other antigens of the panel. These results strongly suggest that in SLE sera there are at least three populations of circulating anti-DNA antibodies: those strictly specific for DNA, those recognizing DNA and TNP and those recognizing DNA and other macromolecules. Furthermore, because six out of nine of the eluates contained antibodies with an absolute or restricted specificity for DNA, this suggests that these antibodies are more often pathogenic than the polyspecific ones recognizing DNA and other macromolecules." @default.
• W154177512 created "2016-06-24" @default.
• W154177512 creator A5022424732 @default.
• W154177512 creator A5025793523 @default.
• W154177512 creator A5036884711 @default.
• W154177512 creator A5044076763 @default.
• W154177512 creator A5063250291 @default.
• W154177512 date "1987-07-01" @default.
• W154177512 modified "2023-09-23" @default.
• W154177512 title "Natural autoantibodies in systemic lupus erythematosus." @default.
• W154177512 cites W122667831 @default.
• W154177512 cites W1518592509 @default.
• W154177512 cites W1538692246 @default.
• W154177512 cites W1579753223 @default.
• W154177512 cites W1586996792 @default.
• W154177512 cites W1590058201 @default.
• W154177512 cites W1597017834 @default.
• W154177512 cites W160997634 @default.
• W154177512 cites W1624366049 @default.
• W154177512 cites W193688223 @default.
• W154177512 cites W1973685164 @default.
• W154177512 cites W1991708964 @default.
• W154177512 cites W1992822332 @default.
• W154177512 cites W1997133987 @default.
• W154177512 cites W2010664601 @default.
• W154177512 cites W2013909312 @default.
• W154177512 cites W2014636427 @default.
• W154177512 cites W2021919631 @default.
• W154177512 cites W2059300566 @default.
• W154177512 cites W2062719651 @default.
• W154177512 cites W2066057376 @default.
• W154177512 cites W2070610465 @default.
• W154177512 cites W2134666735 @default.
• W154177512 cites W2139790922 @default.
• W154177512 cites W2146203649 @default.
• W154177512 cites W2160209304 @default.
• W154177512 cites W2165449027 @default.
• W154177512 cites W2272276626 @default.
• W154177512 cites W2418159305 @default.
• W154177512 cites W307316280 @default.
• W154177512 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1542235" @default.
• W154177512 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3498588" @default.
• W154177512 hasPublicationYear "1987" @default.
• W154177512 type Work @default.
• W154177512 sameAs 154177512 @default.
• W154177512 citedByCount "23" @default.
• W154177512 countsByYear W1541775122013 @default.
• W154177512 countsByYear W1541775122015 @default.
• W154177512 countsByYear W1541775122018 @default.
• W154177512 crossrefType "journal-article" @default.
• W154177512 hasAuthorship W154177512A5022424732 @default.
• W154177512 hasAuthorship W154177512A5025793523 @default.
• W154177512 hasAuthorship W154177512A5036884711 @default.
• W154177512 hasAuthorship W154177512A5044076763 @default.
• W154177512 hasAuthorship W154177512A5063250291 @default.
• W154177512 hasConcept C142724271 @default.
• W154177512 hasConcept C147483822 @default.
• W154177512 hasConcept C159654299 @default.
• W154177512 hasConcept C163764329 @default.
• W154177512 hasConcept C203014093 @default.
• W154177512 hasConcept C2775915377 @default.
• W154177512 hasConcept C2776912625 @default.
• W154177512 hasConcept C2779134260 @default.
• W154177512 hasConcept C2779912601 @default.
• W154177512 hasConcept C552990157 @default.
• W154177512 hasConcept C55493867 @default.
• W154177512 hasConcept C71924100 @default.
• W154177512 hasConcept C86803240 @default.
• W154177512 hasConceptScore W154177512C142724271 @default.
• W154177512 hasConceptScore W154177512C147483822 @default.
• W154177512 hasConceptScore W154177512C159654299 @default.
• W154177512 hasConceptScore W154177512C163764329 @default.
• W154177512 hasConceptScore W154177512C203014093 @default.
• W154177512 hasConceptScore W154177512C2775915377 @default.
• W154177512 hasConceptScore W154177512C2776912625 @default.
• W154177512 hasConceptScore W154177512C2779134260 @default.
• W154177512 hasConceptScore W154177512C2779912601 @default.
• W154177512 hasConceptScore W154177512C552990157 @default.
• W154177512 hasConceptScore W154177512C55493867 @default.
• W154177512 hasConceptScore W154177512C71924100 @default.
• W154177512 hasConceptScore W154177512C86803240 @default.
• W154177512 hasIssue "1" @default.
• W154177512 hasLocation W1541775121 @default.
• W154177512 hasOpenAccess W154177512 @default.
• W154177512 hasPrimaryLocation W1541775121 @default.
• W154177512 hasRelatedWork W1452338814 @default.
• W154177512 hasRelatedWork W1896534392 @default.
• W154177512 hasRelatedWork W2049247148 @default.
• W154177512 hasRelatedWork W2051005234 @default.
• W154177512 hasRelatedWork W2108207992 @default.
• W154177512 hasRelatedWork W2116971739 @default.
• W154177512 hasRelatedWork W2123011632 @default.
• W154177512 hasRelatedWork W2149857280 @default.
• W154177512 hasRelatedWork W2479161934 @default.
• W154177512 hasRelatedWork W2743180980 @default.
• W154177512 hasVolume "69" @default.
• W154177512 isParatext "false" @default.
• W154177512 isRetracted "false" @default.

• next