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- W1541954835 endingPage "185" @default.
- W1541954835 startingPage "185" @default.
- W1541954835 abstract "Influencing the progression of COPD has long been an elusive goal of drug therapy. Directly or indirectly, this has again been investigated in two of the largest, long-term drug trials in COPD: Towards a Revolution in COPD Health (TORCH) and Understanding Potential Long-Term Impacts on Function with Tiotropium (UPLIFT). Neither trial achieved statistical significance in their respective primary outcomes; however, both make considerable contributions to understanding of how the progression of COPD may be influenced. The objective of this article is to review the data from these different trials with a view to what can be learnt about the management of COPD. The long-term improvements in lung function, health-related quality of life, and possibly survival from the use of long-acting bronchodilators in these trials suggest an influence on progression of the disease. With the more optimistic view of benefits from drug treatment of COPD that these trials provide, a review of prescribing practices is warranted." @default.
- W1541954835 created "2016-06-24" @default.
- W1541954835 creator A5052712328 @default.
- W1541954835 creator A5071831143 @default.
- W1541954835 date "2009-05-01" @default.
- W1541954835 modified "2023-09-27" @default.
- W1541954835 title "Insights into interventions in managing COPD patients: lessons from the TORCH and UPLIFT® studies" @default.
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- W1541954835 doi "https://doi.org/10.2147/copd.s4270" @default.
- W1541954835 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2685145" @default.
- W1541954835 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19516917" @default.
- W1541954835 hasPublicationYear "2009" @default.
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