Matches in SemOpenAlex for { <https://semopenalex.org/work/W1542123466> ?p ?o ?g. }
- W1542123466 endingPage "71" @default.
- W1542123466 startingPage "58" @default.
- W1542123466 abstract "p63 and p73 share significant structural and functional homologies with the tumour suppressor p53. Unlike the p53 gene, both encode for several isoforms which vary in their NH2 and COOH termini with variable and, in part, opposed biological functions. The objective of the present study was to analyse the expression profiles of p53 family members in squamous cell carcinomas of the head and neck (HNSCC) and their alterations caused by exposure to the clinically active drug cisplatin. Using multiplex RT-PCR combined with the Southern technique, we determined transcription of p53 family members in 10 established HNSCC cell lines. In the majority of HNSCC, p53 and different p63/p73 isoforms were expressed with cell-line-specific patterns for composition and intensity of transcript expression. Exposure to cisplatin caused multiple alterations in the p63 and p73 profiles suggesting a complex regulation which may influence the sensitivity to chemotherapy." @default.
- W1542123466 created "2016-06-24" @default.
- W1542123466 creator A5003601361 @default.
- W1542123466 creator A5013320097 @default.
- W1542123466 creator A5076703927 @default.
- W1542123466 creator A5083143288 @default.
- W1542123466 date "2004-01-01" @default.
- W1542123466 modified "2023-09-25" @default.
- W1542123466 title "p53, p63 and p73 Expression in Squamous Cell Carcinomas of the Head and Neck and Their Response to Cisplatin Exposure" @default.
- W1542123466 cites W1482923899 @default.
- W1542123466 cites W1502887285 @default.
- W1542123466 cites W1520122908 @default.
- W1542123466 cites W1531240647 @default.
- W1542123466 cites W1534987406 @default.
- W1542123466 cites W1581569435 @default.
- W1542123466 cites W1590583667 @default.
- W1542123466 cites W1650797637 @default.
- W1542123466 cites W1660800498 @default.
- W1542123466 cites W1878744102 @default.
- W1542123466 cites W1939117974 @default.
- W1542123466 cites W1966292443 @default.
- W1542123466 cites W1985064409 @default.
- W1542123466 cites W1986213213 @default.
- W1542123466 cites W1987026408 @default.
- W1542123466 cites W1997222931 @default.
- W1542123466 cites W1997402112 @default.
- W1542123466 cites W1998068165 @default.
- W1542123466 cites W2014938226 @default.
- W1542123466 cites W2055394616 @default.
- W1542123466 cites W2059630420 @default.
- W1542123466 cites W2061102940 @default.
- W1542123466 cites W2062364714 @default.
- W1542123466 cites W2068445514 @default.
- W1542123466 cites W2070591283 @default.
- W1542123466 cites W2072013516 @default.
- W1542123466 cites W2082180646 @default.
- W1542123466 cites W2087216590 @default.
- W1542123466 cites W2090494026 @default.
- W1542123466 cites W2107203451 @default.
- W1542123466 cites W2107318442 @default.
- W1542123466 cites W2112881364 @default.
- W1542123466 cites W2126787895 @default.
- W1542123466 cites W2141375360 @default.
- W1542123466 cites W2165454946 @default.
- W1542123466 cites W2168211018 @default.
- W1542123466 cites W2317760542 @default.
- W1542123466 cites W2320583977 @default.
- W1542123466 cites W2428600920 @default.
- W1542123466 cites W2474195763 @default.
- W1542123466 doi "https://doi.org/10.1159/000082473" @default.
- W1542123466 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15608418" @default.
- W1542123466 hasPublicationYear "2004" @default.
- W1542123466 type Work @default.
- W1542123466 sameAs 1542123466 @default.
- W1542123466 citedByCount "8" @default.
- W1542123466 countsByYear W15421234662012 @default.
- W1542123466 countsByYear W15421234662017 @default.
- W1542123466 countsByYear W15421234662022 @default.
- W1542123466 crossrefType "book-chapter" @default.
- W1542123466 hasAuthorship W1542123466A5003601361 @default.
- W1542123466 hasAuthorship W1542123466A5013320097 @default.
- W1542123466 hasAuthorship W1542123466A5076703927 @default.
- W1542123466 hasAuthorship W1542123466A5083143288 @default.
- W1542123466 hasConcept C104317684 @default.
- W1542123466 hasConcept C121608353 @default.
- W1542123466 hasConcept C143998085 @default.
- W1542123466 hasConcept C1491633281 @default.
- W1542123466 hasConcept C2776530083 @default.
- W1542123466 hasConcept C2776694085 @default.
- W1542123466 hasConcept C2776833033 @default.
- W1542123466 hasConcept C2778239845 @default.
- W1542123466 hasConcept C2778264664 @default.
- W1542123466 hasConcept C502942594 @default.
- W1542123466 hasConcept C53345823 @default.
- W1542123466 hasConcept C54355233 @default.
- W1542123466 hasConcept C555283112 @default.
- W1542123466 hasConcept C71924100 @default.
- W1542123466 hasConcept C81885089 @default.
- W1542123466 hasConcept C86803240 @default.
- W1542123466 hasConceptScore W1542123466C104317684 @default.
- W1542123466 hasConceptScore W1542123466C121608353 @default.
- W1542123466 hasConceptScore W1542123466C143998085 @default.
- W1542123466 hasConceptScore W1542123466C1491633281 @default.
- W1542123466 hasConceptScore W1542123466C2776530083 @default.
- W1542123466 hasConceptScore W1542123466C2776694085 @default.
- W1542123466 hasConceptScore W1542123466C2776833033 @default.
- W1542123466 hasConceptScore W1542123466C2778239845 @default.
- W1542123466 hasConceptScore W1542123466C2778264664 @default.
- W1542123466 hasConceptScore W1542123466C502942594 @default.
- W1542123466 hasConceptScore W1542123466C53345823 @default.
- W1542123466 hasConceptScore W1542123466C54355233 @default.
- W1542123466 hasConceptScore W1542123466C555283112 @default.
- W1542123466 hasConceptScore W1542123466C71924100 @default.
- W1542123466 hasConceptScore W1542123466C81885089 @default.
- W1542123466 hasConceptScore W1542123466C86803240 @default.
- W1542123466 hasLocation W15421234661 @default.
- W1542123466 hasLocation W15421234662 @default.
- W1542123466 hasOpenAccess W1542123466 @default.