Matches in SemOpenAlex for { <https://semopenalex.org/work/W154222406> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W154222406 endingPage "224" @default.
- W154222406 startingPage "220" @default.
- W154222406 abstract "Alternative polyadenylation is a key regulatory process which affects the 3' end formation of variants of the same transcription unit, thus altering gene expression pattern, and transcripts' cellular behaviour and characteristics. The common methodology for computational analysis of alternative polyadenylation signal utilization is based on EST data, specifically on PolyA/PolyT tailed ESTs. Studying the human ESTs dataset we detected a significant underrepresentation of PolyA/PolyT tailed ESTs, constituting only 10% of most libraries. Consequently, more than 50% of false-negative events are revealed in the analysis of alternatively polyadenylated variants' expression. We therefore argue that the ratios of PolyA/PolyT tailed ESTs, as represented in the human EST database, do not reflect the truepicture of 3' end variants formation of a given physiological situation. Thus the EST database should not be considered a reliable source for alternative polyadenylation signal usage inference." @default.
- W154222406 created "2016-06-24" @default.
- W154222406 creator A5008446762 @default.
- W154222406 creator A5033903901 @default.
- W154222406 creator A5046207682 @default.
- W154222406 creator A5049352361 @default.
- W154222406 date "2006-10-07" @default.
- W154222406 modified "2023-09-23" @default.
- W154222406 title "Under-representation of PolyA/PolyT tailed ESTs in human ESTdb: an obstacle to alternative polyadenylation inference." @default.
- W154222406 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1891686" @default.
- W154222406 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17597892" @default.
- W154222406 hasPublicationYear "2006" @default.
- W154222406 type Work @default.
- W154222406 sameAs 154222406 @default.
- W154222406 citedByCount "1" @default.
- W154222406 crossrefType "journal-article" @default.
- W154222406 hasAuthorship W154222406A5008446762 @default.
- W154222406 hasAuthorship W154222406A5033903901 @default.
- W154222406 hasAuthorship W154222406A5046207682 @default.
- W154222406 hasAuthorship W154222406A5049352361 @default.
- W154222406 hasConcept C104317684 @default.
- W154222406 hasConcept C142575336 @default.
- W154222406 hasConcept C149034497 @default.
- W154222406 hasConcept C150194340 @default.
- W154222406 hasConcept C154945302 @default.
- W154222406 hasConcept C2776214188 @default.
- W154222406 hasConcept C41008148 @default.
- W154222406 hasConcept C54355233 @default.
- W154222406 hasConcept C70721500 @default.
- W154222406 hasConcept C86803240 @default.
- W154222406 hasConceptScore W154222406C104317684 @default.
- W154222406 hasConceptScore W154222406C142575336 @default.
- W154222406 hasConceptScore W154222406C149034497 @default.
- W154222406 hasConceptScore W154222406C150194340 @default.
- W154222406 hasConceptScore W154222406C154945302 @default.
- W154222406 hasConceptScore W154222406C2776214188 @default.
- W154222406 hasConceptScore W154222406C41008148 @default.
- W154222406 hasConceptScore W154222406C54355233 @default.
- W154222406 hasConceptScore W154222406C70721500 @default.
- W154222406 hasConceptScore W154222406C86803240 @default.
- W154222406 hasIssue "6" @default.
- W154222406 hasLocation W1542224061 @default.
- W154222406 hasLocation W1542224062 @default.
- W154222406 hasOpenAccess W154222406 @default.
- W154222406 hasPrimaryLocation W1542224061 @default.
- W154222406 hasRelatedWork W2009988114 @default.
- W154222406 hasRelatedWork W2016027155 @default.
- W154222406 hasRelatedWork W2030573509 @default.
- W154222406 hasRelatedWork W2050280984 @default.
- W154222406 hasRelatedWork W2055247169 @default.
- W154222406 hasRelatedWork W2068125297 @default.
- W154222406 hasRelatedWork W2076299503 @default.
- W154222406 hasRelatedWork W2087865269 @default.
- W154222406 hasRelatedWork W2096720270 @default.
- W154222406 hasRelatedWork W2103635790 @default.
- W154222406 hasRelatedWork W2123759220 @default.
- W154222406 hasRelatedWork W2139344056 @default.
- W154222406 hasRelatedWork W2151513786 @default.
- W154222406 hasRelatedWork W2154583350 @default.
- W154222406 hasRelatedWork W2791189508 @default.
- W154222406 hasRelatedWork W2949671734 @default.
- W154222406 hasRelatedWork W3176588395 @default.
- W154222406 hasRelatedWork W3184554417 @default.
- W154222406 hasRelatedWork W3192081375 @default.
- W154222406 hasRelatedWork W44767279 @default.
- W154222406 hasVolume "1" @default.
- W154222406 isParatext "false" @default.
- W154222406 isRetracted "false" @default.
- W154222406 magId "154222406" @default.
- W154222406 workType "article" @default.