FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1542224370> ?p ?o ?g. }

• W1542224370 endingPage "1837" @default.
• W1542224370 startingPage "1828" @default.
• W1542224370 abstract "Binding of three Bacillus thuringiensis insecticidal crystal proteins (ICPs) to the midgut epithelium of Ostrinia nubilalis larvae was characterized by performing binding experiments with both isolated brush border membrane vesicles and gut tissue sections. Our results demonstrate that two independent ICP receptors are present in the brush border of O. nubilalis gut epithelium. From competition binding experiments performed with 125 I-labeled and native ICPs it was concluded that CryIA(b) and CryIA(c) are recognized by the same receptor. An 11-fold-higher binding affinity of CryIA(b) for this receptor correlated with a 10-fold-higher toxicity of this ICP compared with CryIA(c). The CryIB toxin did not compete for the binding site of CryIA(b) and CryIA(c). Immunological detection of ingested B. thuringiensis ICPs on gut sections of O. nubilalis larvae revealed binding only along the epithelial brush border membrane. CryID and CryIE, two ICPs that are not toxic to O. nubilalis, were not bound to the apical microvilli of gut epithelial cells. In vitro binding experiments performed with native and biotinylated ICPs on tissue sections confirmed the correlation between ICP binding and toxicity. Moreover, by performing heterologous competition experiments with biotinylated and native ICPs, it was confirmed that the CryIB receptor is different from the receptor for CryIA(b) and CryIA(c). Retention of activated crystal proteins by the peritrophic membrane was not correlated with toxicity. Furthermore, it was demonstrated that CryIA(b), CryIA(c), and CryIB toxins interact in vitro with the epithelial microvilli of Malpighian tubules. In addition, CryIA(c) toxin also adheres to the basement membrane of the midgut epithelium." @default.
• W1542224370 created "2016-06-24" @default.
• W1542224370 creator A5045541568 @default.
• W1542224370 creator A5048648951 @default.
• W1542224370 creator A5056871325 @default.
• W1542224370 creator A5077237725 @default.
• W1542224370 creator A5091609697 @default.
• W1542224370 date "1993-06-01" @default.
• W1542224370 modified "2023-09-26" @default.
• W1542224370 title "Two Different <i>Bacillus thuringiensis</i> Delta-Endotoxin Receptors in the Midgut Brush Border Membrane of the European Corn Borer, <i>Ostrinia nubilalis</i> (Hübner) (Lepidoptera: Pyralidae)" @default.
• W1542224370 cites W1508363397 @default.
• W1542224370 cites W1593307737 @default.
• W1542224370 cites W1659137474 @default.
• W1542224370 cites W1752586708 @default.
• W1542224370 cites W1965068105 @default.
• W1542224370 cites W1978045508 @default.
• W1542224370 cites W1986913309 @default.
• W1542224370 cites W2004813753 @default.
• W1542224370 cites W2007879139 @default.
• W1542224370 cites W2022824956 @default.
• W1542224370 cites W2024018480 @default.
• W1542224370 cites W2028702790 @default.
• W1542224370 cites W2041836153 @default.
• W1542224370 cites W2043813981 @default.
• W1542224370 cites W2062087578 @default.
• W1542224370 cites W2070207092 @default.
• W1542224370 cites W2071864393 @default.
• W1542224370 cites W2076372937 @default.
• W1542224370 cites W2079893722 @default.
• W1542224370 cites W2080580789 @default.
• W1542224370 cites W2090091975 @default.
• W1542224370 cites W2093732305 @default.
• W1542224370 cites W2100837269 @default.
• W1542224370 cites W2131430628 @default.
• W1542224370 cites W2167992317 @default.
• W1542224370 cites W2170577949 @default.
• W1542224370 cites W2531527210 @default.
• W1542224370 cites W4293247451 @default.
• W1542224370 doi "https://doi.org/10.1128/aem.59.6.1828-1837.1993" @default.
• W1542224370 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/182168" @default.
• W1542224370 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16348960" @default.
• W1542224370 hasPublicationYear "1993" @default.
• W1542224370 type Work @default.
• W1542224370 sameAs 1542224370 @default.
• W1542224370 citedByCount "84" @default.
• W1542224370 countsByYear W15422243702012 @default.
• W1542224370 countsByYear W15422243702013 @default.
• W1542224370 countsByYear W15422243702014 @default.
• W1542224370 countsByYear W15422243702015 @default.
• W1542224370 countsByYear W15422243702017 @default.
• W1542224370 countsByYear W15422243702019 @default.
• W1542224370 countsByYear W15422243702023 @default.
• W1542224370 crossrefType "journal-article" @default.
• W1542224370 hasAuthorship W1542224370A5045541568 @default.
• W1542224370 hasAuthorship W1542224370A5048648951 @default.
• W1542224370 hasAuthorship W1542224370A5056871325 @default.
• W1542224370 hasAuthorship W1542224370A5077237725 @default.
• W1542224370 hasAuthorship W1542224370A5091609697 @default.
• W1542224370 hasBestOaLocation W15422243701 @default.
• W1542224370 hasConcept C130316041 @default.
• W1542224370 hasConcept C150149183 @default.
• W1542224370 hasConcept C153911025 @default.
• W1542224370 hasConcept C173758957 @default.
• W1542224370 hasConcept C177756618 @default.
• W1542224370 hasConcept C2776776645 @default.
• W1542224370 hasConcept C2777716713 @default.
• W1542224370 hasConcept C2779035793 @default.
• W1542224370 hasConcept C2781138550 @default.
• W1542224370 hasConcept C41625074 @default.
• W1542224370 hasConcept C523546767 @default.
• W1542224370 hasConcept C5426402 @default.
• W1542224370 hasConcept C54355233 @default.
• W1542224370 hasConcept C55493867 @default.
• W1542224370 hasConcept C59822182 @default.
• W1542224370 hasConcept C86803240 @default.
• W1542224370 hasConcept C89423630 @default.
• W1542224370 hasConceptScore W1542224370C130316041 @default.
• W1542224370 hasConceptScore W1542224370C150149183 @default.
• W1542224370 hasConceptScore W1542224370C153911025 @default.
• W1542224370 hasConceptScore W1542224370C173758957 @default.
• W1542224370 hasConceptScore W1542224370C177756618 @default.
• W1542224370 hasConceptScore W1542224370C2776776645 @default.
• W1542224370 hasConceptScore W1542224370C2777716713 @default.
• W1542224370 hasConceptScore W1542224370C2779035793 @default.
• W1542224370 hasConceptScore W1542224370C2781138550 @default.
• W1542224370 hasConceptScore W1542224370C41625074 @default.
• W1542224370 hasConceptScore W1542224370C523546767 @default.
• W1542224370 hasConceptScore W1542224370C5426402 @default.
• W1542224370 hasConceptScore W1542224370C54355233 @default.
• W1542224370 hasConceptScore W1542224370C55493867 @default.
• W1542224370 hasConceptScore W1542224370C59822182 @default.
• W1542224370 hasConceptScore W1542224370C86803240 @default.
• W1542224370 hasConceptScore W1542224370C89423630 @default.
• W1542224370 hasIssue "6" @default.
• W1542224370 hasLocation W15422243701 @default.
• W1542224370 hasLocation W15422243702 @default.
• W1542224370 hasLocation W15422243703 @default.
• W1542224370 hasOpenAccess W1542224370 @default.

• next