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- W1542233750 abstract "A quarter of the world's population is thought to be deficient in iron. Though the functional effects of iron deficiency have been studied in infancy and adulthood, adolescence, a period of significant neural and behavioral maturation, has not received much attention. In this cross-sectional analysis of Indian adolescents in rural Maharashtra (n = 147; 12–16 y; 61 females), relations between baseline blood variables and performance on a test of simple reaction time (SRT, in ms, one of a set of five measures of perceptual and cognitive functioning) were examined. Iron status was defined according to stage of iron deficiency (iron-deficient anemic (IDA), iron-deficient (ID), iron sufficient (IS)). Those in the IDA and ID groups had longer RT than those in the IS group (p=0.005 & 0.013, respectively). SRT for individuals who were anemic but not ID did not differ from those of the IS group but were faster than those in the IDA and ID groups (both p<0.01). Further analyses revealed that the serum ferritin quartile was strongly related to SRT (p<0.001) whereas hemoglobin quartile was not. Finally, those with positive body iron (calculated by Cook's equation) had shorter SRTs than those with negative body iron (p=0.044). We conclude that iron deficiency with or without anemia is associated with slower responding, whereas anemia in the absence of iron deficiency is unrelated to response speed in Indian adolescents. Grant Funding Source: HarvestPlus" @default.
- W1542233750 created "2016-06-24" @default.
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- W1542233750 date "2013-04-01" @default.
- W1542233750 modified "2023-09-27" @default.
- W1542233750 title "Iron deficiency but not anemia affects cognition in Indian adolescents" @default.
- W1542233750 doi "https://doi.org/10.1096/fasebj.27.1_supplement.845.8" @default.
- W1542233750 hasPublicationYear "2013" @default.
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