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- W1542439312 endingPage "350" @default.
- W1542439312 startingPage "269" @default.
- W1542439312 abstract "A lot of anticancerous agents have been isolated from natural sources, especially from microorganisms and plants. However, there is no special type of compound for cancer therapy. Various types of substances are effective for various types of cancers and tumors, for instance, alkaloids, lignans, terpenes, and steroids. This chapter focuses on the antitumor compounds isolated from higher plants. The development of clinically useful anticancer agents is dependent on screening system and sample sources for the bioassay. The search for potential anticancer agents from natural sources has mainly utilized bioassays confirmed by the National Cancer Institute (NCI), because the large number of natural products screened by the NCI program has enabled the assessment of the relationship between experimental animals and clinical patients for drug development, and screening protocols for each tumor system have been well established. Recently, NCI has established a disease-oriented approach to antitumor activity screening, the biological response modifiers (BRM) program, which takes into account the diversity and specificity of tumor, and the requirements of novel structure types and novel action-mechanistic types of anticancer agents." @default.
- W1542439312 created "2016-06-24" @default.
- W1542439312 creator A5009563173 @default.
- W1542439312 creator A5010572349 @default.
- W1542439312 creator A5031293404 @default.
- W1542439312 creator A5087590469 @default.
- W1542439312 date "2000-01-01" @default.
- W1542439312 modified "2023-10-15" @default.
- W1542439312 title "Anti Tumor Compounds Isolated from Higher Plants" @default.
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