FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1542719901> ?p ?o ?g. }

• W1542719901 endingPage "97" @default.
• W1542719901 startingPage "81" @default.
• W1542719901 abstract "TGF-β proteins are produced as latent, high molecular weight complexes. The latent form of TGF-β1 (L-TGF-β1) in human platelets comprises three components: the mature TGF-β1 molecule, the N-terminal remnant of the TGF-β1 precursor in dimeric form and a novel component denoted TGF-β1-binding protein (TGF-β1-BP). Recombinant TGF-β1 expressed in CHO cells, which lacks TGF-β1-BP, is also produced as a latent form. Thus, the N-terminal remnant of the TGF-β1 precursor is sufficient for TGF-β1 latency, and it was denoted TGF-β1 latency-associated peptide (TGF-β1-LAP). The cDNA for TGF-β1-BP has been cloned. It is mainly composed of two different kinds of repeat sequences, i.e. 16 epidermal growth factor-like repeats and three copies of a cysteine-rich repeat hitherto not found in other proteins. The function of TGF-β1-BP remains to be elucidated. Activation of L-TGF-β can be achieved by different chemical and enzymic treatments, or by incubation with certain cell types. Understanding of the physiological activation mechanisms and the in vivo roles of L-TGF-β will be important for future clinical applications of TGF-β." @default.
• W1542719901 created "2016-06-24" @default.
• W1542719901 creator A5051009186 @default.
• W1542719901 creator A5084535456 @default.
• W1542719901 date "2007-09-28" @default.
• W1542719901 modified "2023-10-17" @default.
• W1542719901 title "Latent forms of TGF‐β: Molecular Structure and Mechanisms of Activation" @default.
• W1542719901 cites W1494827648 @default.
• W1542719901 cites W1528827595 @default.
• W1542719901 cites W1560768456 @default.
• W1542719901 cites W1593006334 @default.
• W1542719901 cites W1600868878 @default.
• W1542719901 cites W1894312995 @default.
• W1542719901 cites W1973630430 @default.
• W1542719901 cites W1984172347 @default.
• W1542719901 cites W1987568997 @default.
• W1542719901 cites W1989897445 @default.
• W1542719901 cites W1997886082 @default.
• W1542719901 cites W1998354909 @default.
• W1542719901 cites W1999446763 @default.
• W1542719901 cites W2002621910 @default.
• W1542719901 cites W2012165500 @default.
• W1542719901 cites W2017464562 @default.
• W1542719901 cites W2018827318 @default.
• W1542719901 cites W2027726633 @default.
• W1542719901 cites W2039299132 @default.
• W1542719901 cites W2042965746 @default.
• W1542719901 cites W2057848088 @default.
• W1542719901 cites W2058892394 @default.
• W1542719901 cites W2073865988 @default.
• W1542719901 cites W2086833378 @default.
• W1542719901 cites W2088854697 @default.
• W1542719901 cites W2092671785 @default.
• W1542719901 cites W2096525503 @default.
• W1542719901 cites W2150472477 @default.
• W1542719901 cites W2155383324 @default.
• W1542719901 cites W2161454032 @default.
• W1542719901 cites W2164279207 @default.
• W1542719901 cites W4211166816 @default.
• W1542719901 cites W4229906000 @default.
• W1542719901 cites W4239324416 @default.
• W1542719901 doi "https://doi.org/10.1002/9780470514061.ch6" @default.
• W1542719901 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2070685" @default.
• W1542719901 hasPublicationYear "2007" @default.
• W1542719901 type Work @default.
• W1542719901 sameAs 1542719901 @default.
• W1542719901 citedByCount "26" @default.
• W1542719901 countsByYear W15427199012014 @default.
• W1542719901 countsByYear W15427199012015 @default.
• W1542719901 countsByYear W15427199012016 @default.
• W1542719901 countsByYear W15427199012017 @default.
• W1542719901 countsByYear W15427199012019 @default.
• W1542719901 countsByYear W15427199012020 @default.
• W1542719901 countsByYear W15427199012021 @default.
• W1542719901 countsByYear W15427199012022 @default.
• W1542719901 crossrefType "other" @default.
• W1542719901 hasAuthorship W1542719901A5051009186 @default.
• W1542719901 hasAuthorship W1542719901A5084535456 @default.
• W1542719901 hasConcept C104317684 @default.
• W1542719901 hasConcept C118131993 @default.
• W1542719901 hasConcept C125555471 @default.
• W1542719901 hasConcept C153911025 @default.
• W1542719901 hasConcept C170493617 @default.
• W1542719901 hasConcept C185592680 @default.
• W1542719901 hasConcept C187882448 @default.
• W1542719901 hasConcept C2775960820 @default.
• W1542719901 hasConcept C2779281246 @default.
• W1542719901 hasConcept C40767141 @default.
• W1542719901 hasConcept C55493867 @default.
• W1542719901 hasConcept C86803240 @default.
• W1542719901 hasConcept C95444343 @default.
• W1542719901 hasConceptScore W1542719901C104317684 @default.
• W1542719901 hasConceptScore W1542719901C118131993 @default.
• W1542719901 hasConceptScore W1542719901C125555471 @default.
• W1542719901 hasConceptScore W1542719901C153911025 @default.
• W1542719901 hasConceptScore W1542719901C170493617 @default.
• W1542719901 hasConceptScore W1542719901C185592680 @default.
• W1542719901 hasConceptScore W1542719901C187882448 @default.
• W1542719901 hasConceptScore W1542719901C2775960820 @default.
• W1542719901 hasConceptScore W1542719901C2779281246 @default.
• W1542719901 hasConceptScore W1542719901C40767141 @default.
• W1542719901 hasConceptScore W1542719901C55493867 @default.
• W1542719901 hasConceptScore W1542719901C86803240 @default.
• W1542719901 hasConceptScore W1542719901C95444343 @default.
• W1542719901 hasLocation W15427199011 @default.
• W1542719901 hasLocation W15427199012 @default.
• W1542719901 hasOpenAccess W1542719901 @default.
• W1542719901 hasPrimaryLocation W15427199011 @default.
• W1542719901 hasRelatedWork W120375644 @default.
• W1542719901 hasRelatedWork W1536051969 @default.
• W1542719901 hasRelatedWork W2043328301 @default.
• W1542719901 hasRelatedWork W2076190284 @default.
• W1542719901 hasRelatedWork W2095850742 @default.
• W1542719901 hasRelatedWork W2351582911 @default.
• W1542719901 hasRelatedWork W2922064785 @default.
• W1542719901 hasRelatedWork W4229606914 @default.
• W1542719901 hasRelatedWork W4241255068 @default.
• W1542719901 hasRelatedWork W2098250766 @default.

• next