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- W1542829069 abstract "This chapter reviews that poliomyelitis is a monophasic illness affecting lower motor neurons and individuals may describe new problems years after the initial weakness. It studies 38 people with the post-polio syndrome over a 15-year period assessing a number of neuromuscular measures, including motor unit number estimation (MUNE). There is a modest decline in summated compound muscle action potential and a more prominent decline in the summated motor unit number estimates. The late deterioration in strength is rather associated with the magnitude of the residual deficits than magnitude of decline and is partially accounted for by concomitant, non-neurological disorders. The better prediction of progressing weakness by a natural log rather than a linear model of decline in the number of motor units are likely due to the redundancy of motor units and capacity for collateral sprouting. Twenty-five individuals reported progressive weakness, but there was no objective change in MUNE and other measures. There was an association with reported weakness and initial deficits. There was a slow decline in MUNE values over time in both the groups." @default.
- W1542829069 created "2016-06-24" @default.
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- W1542829069 date "2009-01-01" @default.
- W1542829069 modified "2023-09-27" @default.
- W1542829069 title "Prospective 15-year study of neuromuscular function in a cohort of patients with prior poliomyelitis" @default.
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- W1542829069 doi "https://doi.org/10.1016/s1567-424x(08)00020-2" @default.
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