Matches in SemOpenAlex for { <https://semopenalex.org/work/W1542961153> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W1542961153 endingPage "64" @default.
- W1542961153 startingPage "59" @default.
- W1542961153 abstract "The pathogenesis of nasal polyposis remains unclear; it severely affects patients' quality of life and complicates inflammation in adjacent organs such as sinusitis and asthma. Aberrant immune regulatory function in these patients is proposed. The present study aims to examine the regulatory T cells (T(reg) ) in nasal mucosa of patients with allergic rhinitis (AR) and nasal polyposis (NP). Patients with AR or AR/NP were treated with inferior turbinectomy for their inferior turbinate hyperplasia. Surgically removed nasal mucosa was collected to examine the T(reg) by immunohistochemistry and flow cytometry. The results showed that more forkhead box P3 (FoxP3)(+) cells were found in AR with polyps than in those with AR alone. Further studies revealed that these FoxP3(+) T cells from AR/NP group also expressed interleukin (IL)-17. In vitro study showed that staphylococcal enterotoxin B (SEB) induced CD4(+) FoxP3(+) T cells to become FoxP3(+) IL-17(+) cells via facilitating the expression of IL-6, that in synergy with transforming growth factor-beta, induce the expression of IL-17 in FoxP3(+) cells. We conclude that FoxP3(+) IL-17(+) T cells were localized in the nasal mucosa of patients with AR and NP. SEB may play a role in converting FoxP3(+) T(reg) to FoxP3(+) IL-17(+) T cells. The presence of IL-17(+) FoxP3(+) T cells may play a role in the remodelling of the nasal airways in certain people who develop polyps, irrespective of whether or not they are atopic." @default.
- W1542961153 created "2016-06-24" @default.
- W1542961153 creator A5007473150 @default.
- W1542961153 creator A5013486844 @default.
- W1542961153 creator A5032157786 @default.
- W1542961153 creator A5037053656 @default.
- W1542961153 creator A5041987633 @default.
- W1542961153 creator A5048333692 @default.
- W1542961153 creator A5052338474 @default.
- W1542961153 creator A5063142070 @default.
- W1542961153 date "2010-11-22" @default.
- W1542961153 modified "2023-10-13" @default.
- W1542961153 title "Forkhead box P3+ T cells express interleukin-17 in nasal mucosa of patients with both allergic rhinitis and polyposis" @default.
- W1542961153 cites W1844439101 @default.
- W1542961153 cites W1971769218 @default.
- W1542961153 cites W1982941253 @default.
- W1542961153 cites W2011368430 @default.
- W1542961153 cites W2028839726 @default.
- W1542961153 cites W2038386610 @default.
- W1542961153 cites W2049566452 @default.
- W1542961153 cites W2051447573 @default.
- W1542961153 cites W2060044866 @default.
- W1542961153 cites W2063177917 @default.
- W1542961153 cites W2064244014 @default.
- W1542961153 cites W2064577922 @default.
- W1542961153 cites W2076788419 @default.
- W1542961153 cites W2091230752 @default.
- W1542961153 cites W2092273117 @default.
- W1542961153 cites W2099154245 @default.
- W1542961153 cites W2105088246 @default.
- W1542961153 cites W2116553220 @default.
- W1542961153 cites W2120010406 @default.
- W1542961153 cites W2142877732 @default.
- W1542961153 cites W2150677891 @default.
- W1542961153 cites W2167297937 @default.
- W1542961153 doi "https://doi.org/10.1111/j.1365-2249.2010.04278.x" @default.
- W1542961153 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3010912" @default.
- W1542961153 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21091665" @default.
- W1542961153 hasPublicationYear "2010" @default.
- W1542961153 type Work @default.
- W1542961153 sameAs 1542961153 @default.
- W1542961153 citedByCount "29" @default.
- W1542961153 countsByYear W15429611532012 @default.
- W1542961153 countsByYear W15429611532013 @default.
- W1542961153 countsByYear W15429611532014 @default.
- W1542961153 countsByYear W15429611532015 @default.
- W1542961153 countsByYear W15429611532017 @default.
- W1542961153 countsByYear W15429611532020 @default.
- W1542961153 countsByYear W15429611532022 @default.
- W1542961153 countsByYear W15429611532023 @default.
- W1542961153 crossrefType "journal-article" @default.
- W1542961153 hasAuthorship W1542961153A5007473150 @default.
- W1542961153 hasAuthorship W1542961153A5013486844 @default.
- W1542961153 hasAuthorship W1542961153A5032157786 @default.
- W1542961153 hasAuthorship W1542961153A5037053656 @default.
- W1542961153 hasAuthorship W1542961153A5041987633 @default.
- W1542961153 hasAuthorship W1542961153A5048333692 @default.
- W1542961153 hasAuthorship W1542961153A5052338474 @default.
- W1542961153 hasAuthorship W1542961153A5063142070 @default.
- W1542961153 hasBestOaLocation W15429611531 @default.
- W1542961153 hasConcept C142724271 @default.
- W1542961153 hasConcept C203014093 @default.
- W1542961153 hasConcept C2779727006 @default.
- W1542961153 hasConcept C2781390199 @default.
- W1542961153 hasConcept C59377437 @default.
- W1542961153 hasConcept C71924100 @default.
- W1542961153 hasConcept C8891405 @default.
- W1542961153 hasConceptScore W1542961153C142724271 @default.
- W1542961153 hasConceptScore W1542961153C203014093 @default.
- W1542961153 hasConceptScore W1542961153C2779727006 @default.
- W1542961153 hasConceptScore W1542961153C2781390199 @default.
- W1542961153 hasConceptScore W1542961153C59377437 @default.
- W1542961153 hasConceptScore W1542961153C71924100 @default.
- W1542961153 hasConceptScore W1542961153C8891405 @default.
- W1542961153 hasIssue "1" @default.
- W1542961153 hasLocation W15429611531 @default.
- W1542961153 hasLocation W15429611532 @default.
- W1542961153 hasLocation W15429611533 @default.
- W1542961153 hasOpenAccess W1542961153 @default.
- W1542961153 hasPrimaryLocation W15429611531 @default.
- W1542961153 hasRelatedWork W1986377866 @default.
- W1542961153 hasRelatedWork W2033081851 @default.
- W1542961153 hasRelatedWork W2353490438 @default.
- W1542961153 hasRelatedWork W2371062252 @default.
- W1542961153 hasRelatedWork W2378576706 @default.
- W1542961153 hasRelatedWork W2410911163 @default.
- W1542961153 hasRelatedWork W2465691133 @default.
- W1542961153 hasRelatedWork W3013351791 @default.
- W1542961153 hasRelatedWork W4252097361 @default.
- W1542961153 hasRelatedWork W4313368814 @default.
- W1542961153 hasVolume "163" @default.
- W1542961153 isParatext "false" @default.
- W1542961153 isRetracted "false" @default.
- W1542961153 magId "1542961153" @default.
- W1542961153 workType "article" @default.