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- W1543255520 abstract "This chapter discusses the development beyond the embryo. It describes the methods used to characterize the molecular or genetic signaling events regulating later stages of craniofacial development, including the growth and differentiation of the craniofacial skeleton, and of replacement tooth development. Morphogenesis can be defined as the processes that are responsible for producing the complex shapes of adults from the simple ball of cells that derives from division of the fertilized egg. This chapter illustrates that extensive morphogenetic changes occur after 5 dpf; therefore, the existing challenge for developmental biologists is to extend the current genetic paradigm beyond the embryo. Recently developed tools, including in vivo mineralized tissue stains combined with sensitive GM analyses provide the necessary means to elucidate the molecules and pathways that produce shape in the adult craniofacial skeletal complex. It is likely that the application of these methods for the analyses of later-staged zebrafish development will provide significant insight into the regulation of human craniofacial development." @default.
- W1543255520 created "2016-06-24" @default.
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- W1543255520 date "2004-01-01" @default.
- W1543255520 modified "2023-10-09" @default.
- W1543255520 title "Morphogenesis of the Jaw: Development Beyond the Embryo" @default.
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- W1543255520 doi "https://doi.org/10.1016/s0091-679x(04)76019-7" @default.
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