Matches in SemOpenAlex for { <https://semopenalex.org/work/W1543455908> ?p ?o ?g. }
- W1543455908 endingPage "9356" @default.
- W1543455908 startingPage "9346" @default.
- W1543455908 abstract "The nucleotide sequence of rat carbamyl phosphate synthetase I mRNA has been determined from the complementary DNA. The mRNA comprises minimally 5,645 nucleotides and codes for a polypeptide of 164,564 Da corresponding to the precursor form of the rat liver enzyme. The primary sequence of mature rat carbamyl phosphate synthetase I indicates that the precursor is cleaved at one of two leucines at residues 38 or 39. The derived amino acid sequence of carbamyl phosphate synthetase I is homologous to the sequences of carbamyl phosphate synthetase of Escherichia coli and yeast. The sequence homology extends along the entire length of the rat polypeptide and encompasses the entire sequences of both the small and large subunits of the E. coli and yeast enzymes. The protein sequence data provide strong evidence that the carbamyl phosphate synthetase I gene of rat, the carAB gene of E. coli, and the CPA1 and CPA2 genes of yeast were derived from common ancestral genes. Part of the rat carbamyl phosphate synthetase I gene has been characterized with two nonoverlapping phage clones spanning 28.7 kilobases of rat chromosomal DNA. This region contains 13 exons ranging in size from 68 to 195 base pairs and encodes the 453 carboxyl-terminal amino acids of the rat protein. Southern hybridization analysis of rat genomic DNA indicates the carbamyl phosphate synthetase I gene to be present in single copy." @default.
- W1543455908 created "2016-06-24" @default.
- W1543455908 creator A5017883067 @default.
- W1543455908 creator A5029324979 @default.
- W1543455908 creator A5061138303 @default.
- W1543455908 creator A5081284241 @default.
- W1543455908 date "1985-08-01" @default.
- W1543455908 modified "2023-09-28" @default.
- W1543455908 title "Characterization and derivation of the gene coding for mitochondrial carbamyl phosphate synthetase I of rat." @default.
- W1543455908 cites W1493626606 @default.
- W1543455908 cites W1494587255 @default.
- W1543455908 cites W1517150745 @default.
- W1543455908 cites W1518814649 @default.
- W1543455908 cites W1518942907 @default.
- W1543455908 cites W1524995373 @default.
- W1543455908 cites W153283880 @default.
- W1543455908 cites W1558516755 @default.
- W1543455908 cites W1563025174 @default.
- W1543455908 cites W1579314900 @default.
- W1543455908 cites W1587024655 @default.
- W1543455908 cites W1661624855 @default.
- W1543455908 cites W1668918370 @default.
- W1543455908 cites W1862536219 @default.
- W1543455908 cites W1965051773 @default.
- W1543455908 cites W1969447590 @default.
- W1543455908 cites W1973579483 @default.
- W1543455908 cites W1977728729 @default.
- W1543455908 cites W1985000690 @default.
- W1543455908 cites W1985308458 @default.
- W1543455908 cites W1987484067 @default.
- W1543455908 cites W1995420892 @default.
- W1543455908 cites W2001483662 @default.
- W1543455908 cites W2003399752 @default.
- W1543455908 cites W2005463030 @default.
- W1543455908 cites W2009105413 @default.
- W1543455908 cites W2010131411 @default.
- W1543455908 cites W2010774817 @default.
- W1543455908 cites W2014022982 @default.
- W1543455908 cites W2019410656 @default.
- W1543455908 cites W2026131405 @default.
- W1543455908 cites W2026806554 @default.
- W1543455908 cites W2031573483 @default.
- W1543455908 cites W2075272185 @default.
- W1543455908 cites W2077077811 @default.
- W1543455908 cites W2082571434 @default.
- W1543455908 cites W2118744932 @default.
- W1543455908 cites W2122385641 @default.
- W1543455908 cites W2145557287 @default.
- W1543455908 cites W2415666558 @default.
- W1543455908 cites W2427108809 @default.
- W1543455908 cites W4235401657 @default.
- W1543455908 cites W4246526382 @default.
- W1543455908 doi "https://doi.org/10.1016/s0021-9258(17)39371-7" @default.
- W1543455908 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2991241" @default.
- W1543455908 hasPublicationYear "1985" @default.
- W1543455908 type Work @default.
- W1543455908 sameAs 1543455908 @default.
- W1543455908 citedByCount "157" @default.
- W1543455908 countsByYear W15434559082012 @default.
- W1543455908 countsByYear W15434559082013 @default.
- W1543455908 countsByYear W15434559082014 @default.
- W1543455908 countsByYear W15434559082015 @default.
- W1543455908 countsByYear W15434559082016 @default.
- W1543455908 countsByYear W15434559082017 @default.
- W1543455908 countsByYear W15434559082018 @default.
- W1543455908 countsByYear W15434559082019 @default.
- W1543455908 countsByYear W15434559082023 @default.
- W1543455908 crossrefType "journal-article" @default.
- W1543455908 hasAuthorship W1543455908A5017883067 @default.
- W1543455908 hasAuthorship W1543455908A5029324979 @default.
- W1543455908 hasAuthorship W1543455908A5061138303 @default.
- W1543455908 hasAuthorship W1543455908A5081284241 @default.
- W1543455908 hasBestOaLocation W15434559081 @default.
- W1543455908 hasConcept C104317684 @default.
- W1543455908 hasConcept C153911025 @default.
- W1543455908 hasConcept C181199279 @default.
- W1543455908 hasConcept C185592680 @default.
- W1543455908 hasConcept C2908748535 @default.
- W1543455908 hasConcept C55493867 @default.
- W1543455908 hasConcept C86803240 @default.
- W1543455908 hasConceptScore W1543455908C104317684 @default.
- W1543455908 hasConceptScore W1543455908C153911025 @default.
- W1543455908 hasConceptScore W1543455908C181199279 @default.
- W1543455908 hasConceptScore W1543455908C185592680 @default.
- W1543455908 hasConceptScore W1543455908C2908748535 @default.
- W1543455908 hasConceptScore W1543455908C55493867 @default.
- W1543455908 hasConceptScore W1543455908C86803240 @default.
- W1543455908 hasIssue "16" @default.
- W1543455908 hasLocation W15434559081 @default.
- W1543455908 hasOpenAccess W1543455908 @default.
- W1543455908 hasPrimaryLocation W15434559081 @default.
- W1543455908 hasRelatedWork W1506041082 @default.
- W1543455908 hasRelatedWork W1540178869 @default.
- W1543455908 hasRelatedWork W1990831947 @default.
- W1543455908 hasRelatedWork W2009966535 @default.
- W1543455908 hasRelatedWork W2019988726 @default.
- W1543455908 hasRelatedWork W2038094691 @default.
- W1543455908 hasRelatedWork W2082530227 @default.