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• W1543771029 abstract "A rapid, new procedure for the isolation of intact tonofilaments from newborn rat skins is described. The filament preparations show two major protein subunits on SDS-PAGE with molecular weights of 58000 and 66000 D. An antiserum prepared against the 58000 D protein reacted specifically with the tonofilament preparation, but not with the protein subunits of neurofilaments, glial filaments, tubulin or actin. This specificity is confirmed by indirect immunofluorescence: anti-P58 reacts with the epidermis, whereas antisera against the neurofilament or glial filament proteins and anti-tubulin do not. These data suggest that epidermal filaments represent a class of intermediate filaments distinct from either glial filaments or neurofilaments." @default.
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• W1543771029 date "1980-10-01" @default.
• W1543771029 modified "2023-09-27" @default.
• W1543771029 title "Rapid purification of intact tonofilaments from newborn rats" @default.
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• W1543771029 doi "https://doi.org/10.1016/0014-4827(80)90498-x" @default.
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