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• W1544112911 abstract "Two-thirds to three-quarters of patients with advanced disease from breast and prostate carcinomas have skeletal metastases, and lung, thyroid, and renal carcinoma metastasize to bone in approximately 30% to 40% of cases. Additionally, clinical implications of skeletal metastases include pathological fracture, nerve entrapment and/or spinal cord compression (SCC), bone marrow insufficiency, and hypercalcaemia. Skeletal metastases are the single most frequent indication for palliative radiotherapy. External beam radiotherapy (EBRT) effectively relieves pain from localized sites of skeletal metastases. Treatment with intravenous (IV) injected bone-seeking radiopharmaceuticals (BSRs) is an intriguing alternative that selectively delivers ionizing radiation to targeted areas of amplified osteoblastic activity and targets multiple (symptomatic and asymptomatic) metastases simultaneously. The combination of radiotherapy or radionuclide therapy with bisphosphonates has recently been reviewed." @default.
• W1544112911 created "2016-06-24" @default.
• W1544112911 creator A5035939033 @default.
• W1544112911 creator A5047114036 @default.
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• W1544112911 date "2013-07-19" @default.
• W1544112911 modified "2023-10-10" @default.
• W1544112911 title "Radiotherapy of Skeletal Metastases" @default.
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• W1544112911 doi "https://doi.org/10.1002/9781118453926.ch91" @default.
• W1544112911 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10925615" @default.
• W1544112911 hasPublicationYear "2013" @default.
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