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- W1544165717 abstract "Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. The prevalence of HCC is still increasing in Asia and Africa, and represents a leading cause of death among patients with chronic liver diseases in industrial countries including Europe and North America (Llovet et al., 2003). The prognosis of HCC is considerably poor for following reasons: (1) aggressive treatment for HCC is not usually possible because most of the patients have impaired liver function, (2) hepatoma cells are refractory to standard chemotherapy drugs and radiation, and (3) HCC frequently recurs even after curative resection (Poon et al., 2009). Moreover, owing to the lack of reliable clinical HCC markers, fewer than 20% of patients are diagnosed at a stage where curative treatment can be performed (Llovet et al., 2003)." @default.
- W1544165717 created "2016-06-24" @default.
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- W1544165717 date "2012-02-10" @default.
- W1544165717 modified "2023-10-16" @default.
- W1544165717 title "Molecular Mechanism of DNA Damage Response Pathway During Hepatic Carcinogenesis" @default.
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- W1544165717 doi "https://doi.org/10.5772/29801" @default.
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