FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1544306772> ?p ?o ?g. }

• W1544306772 endingPage "443" @default.
• W1544306772 startingPage "429" @default.
• W1544306772 abstract "Regulation of the bacterial phage-shock-protein (Psp) system involves communication between integral (PspBC) and peripheral (PspA) cytoplasmic membrane proteins and a soluble transcriptional activator (PspF). In this study protein subcellular localization studies were used to distinguish between spatial models for this putative signal transduction pathway in Yersinia enterocolitica. In non-inducing conditions PspA and PspF were almost exclusively in the soluble fraction, consistent with them forming an inhibitory complex in the cytoplasm. However, upon induction PspA, but not PspF, mainly associated with the membrane fraction. This membrane association was dependent on PspBC but independent of increased PspA concentration. Analysis of psp null, overexpression and altered function mutants further supported a model where PspA is predominantly membrane associated only when the system is induced. Activation of the Psp system normally leads to a large increase in PspA concentration and we found that this provided a second mechanism for its membrane association, which did not require PspBC. These data suggest that basal PspFABC protein levels constitute a regulatory switch that moves some PspA to the membrane when an inducing trigger is encountered. Once this switch is activated PspA concentration increases, which might then allow it to directly contact the membrane for its physiological function." @default.
• W1544306772 created "2016-06-24" @default.
• W1544306772 creator A5018255135 @default.
• W1544306772 creator A5033262477 @default.
• W1544306772 creator A5067249700 @default.
• W1544306772 creator A5071463712 @default.
• W1544306772 date "2010-08-31" @default.
• W1544306772 modified "2023-10-15" @default.
• W1544306772 title "Membrane association of PspA depends on activation of the phage-shock-protein response in Yersinia enterocolitica" @default.
• W1544306772 cites W1498884303 @default.
• W1544306772 cites W1534819418 @default.
• W1544306772 cites W1550928296 @default.
• W1544306772 cites W1760445010 @default.
• W1544306772 cites W1901110641 @default.
• W1544306772 cites W1909754684 @default.
• W1544306772 cites W1932830186 @default.
• W1544306772 cites W1937976631 @default.
• W1544306772 cites W1957979928 @default.
• W1544306772 cites W1963576055 @default.
• W1544306772 cites W1964324020 @default.
• W1544306772 cites W1968745789 @default.
• W1544306772 cites W1969784099 @default.
• W1544306772 cites W1981442415 @default.
• W1544306772 cites W1983589176 @default.
• W1544306772 cites W1984388026 @default.
• W1544306772 cites W1997752778 @default.
• W1544306772 cites W2006029448 @default.
• W1544306772 cites W2036436639 @default.
• W1544306772 cites W2041222191 @default.
• W1544306772 cites W2047670590 @default.
• W1544306772 cites W2052164279 @default.
• W1544306772 cites W2053363671 @default.
• W1544306772 cites W2054941036 @default.
• W1544306772 cites W2058081140 @default.
• W1544306772 cites W2058858340 @default.
• W1544306772 cites W2065663947 @default.
• W1544306772 cites W2067799134 @default.
• W1544306772 cites W2078705050 @default.
• W1544306772 cites W2091757194 @default.
• W1544306772 cites W2097932259 @default.
• W1544306772 cites W2097941200 @default.
• W1544306772 cites W2100630678 @default.
• W1544306772 cites W2103070223 @default.
• W1544306772 cites W2104746873 @default.
• W1544306772 cites W2111261116 @default.
• W1544306772 cites W2111887028 @default.
• W1544306772 cites W2120926466 @default.
• W1544306772 cites W2126136756 @default.
• W1544306772 cites W2127966076 @default.
• W1544306772 cites W2131909263 @default.
• W1544306772 cites W2136003736 @default.
• W1544306772 cites W2148817310 @default.
• W1544306772 cites W2160084442 @default.
• W1544306772 cites W2160608142 @default.
• W1544306772 cites W2166665644 @default.
• W1544306772 cites W2172047707 @default.
• W1544306772 doi "https://doi.org/10.1111/j.1365-2958.2010.07344.x" @default.
• W1544306772 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2966024" @default.
• W1544306772 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20979344" @default.
• W1544306772 hasPublicationYear "2010" @default.
• W1544306772 type Work @default.
• W1544306772 sameAs 1544306772 @default.
• W1544306772 citedByCount "36" @default.
• W1544306772 countsByYear W15443067722012 @default.
• W1544306772 countsByYear W15443067722013 @default.
• W1544306772 countsByYear W15443067722014 @default.
• W1544306772 countsByYear W15443067722015 @default.
• W1544306772 countsByYear W15443067722016 @default.
• W1544306772 countsByYear W15443067722017 @default.
• W1544306772 countsByYear W15443067722018 @default.
• W1544306772 countsByYear W15443067722019 @default.
• W1544306772 countsByYear W15443067722021 @default.
• W1544306772 countsByYear W15443067722022 @default.
• W1544306772 countsByYear W15443067722023 @default.
• W1544306772 crossrefType "journal-article" @default.
• W1544306772 hasAuthorship W1544306772A5018255135 @default.
• W1544306772 hasAuthorship W1544306772A5033262477 @default.
• W1544306772 hasAuthorship W1544306772A5067249700 @default.
• W1544306772 hasAuthorship W1544306772A5071463712 @default.
• W1544306772 hasBestOaLocation W15443067721 @default.
• W1544306772 hasConcept C104317684 @default.
• W1544306772 hasConcept C144647389 @default.
• W1544306772 hasConcept C146587185 @default.
• W1544306772 hasConcept C190062978 @default.
• W1544306772 hasConcept C2776234502 @default.
• W1544306772 hasConcept C2776879804 @default.
• W1544306772 hasConcept C41625074 @default.
• W1544306772 hasConcept C523546767 @default.
• W1544306772 hasConcept C54355233 @default.
• W1544306772 hasConcept C547475151 @default.
• W1544306772 hasConcept C55493867 @default.
• W1544306772 hasConcept C86803240 @default.
• W1544306772 hasConcept C88045685 @default.
• W1544306772 hasConcept C95444343 @default.
• W1544306772 hasConceptScore W1544306772C104317684 @default.
• W1544306772 hasConceptScore W1544306772C144647389 @default.
• W1544306772 hasConceptScore W1544306772C146587185 @default.
• W1544306772 hasConceptScore W1544306772C190062978 @default.

• next