FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1544355286> ?p ?o ?g. }

• W1544355286 endingPage "2850" @default.
• W1544355286 startingPage "2839" @default.
• W1544355286 abstract "The peroxisomal enzyme urate oxidase plays a pivotal role in the degradation of purines in both prokaryotes and eukaryotes. However, knowledge about the purine-induced expression of the encoding gene is lacking in vertebrates. These are the first published sequences of fish urate oxidase, which were predicted from PCR amplified liver cDNAs of Atlantic salmon (Salmo salar), Atlantic cod (Gadus morhua), Atlantic halibut (Hippoglossus hippoglossus) and African lungfish (Protopterus annectens). Sequence alignment of different vertebrate urate oxidases revealed amino acid substitutions of putative functional importance in the enzyme of chicken and lungfish. In the adult salmon, expression of urate oxidase mRNA predominated in liver, but was also identified in several nonhepatic organs including brain, but not in skeletal muscle and kidney. Juvenile salmon fed diets containing bacterial protein meal (BPM) rich in nucleic acids showed a significant increase in liver urate oxidase enzyme activity, and urea concentrations in plasma, muscle and liver were elevated. Whereas salmon fed the 18% BPM diet showed a nonsignificant increase in liver mRNA levels of urate oxidase compared with the 0% BPM-fed fish, no further increase in mRNA levels was found in fish receiving 36% BPM. The discrepancy between urate oxidase mRNA and enzyme activity was explained by rapid mRNA degradation or alternatively, post-translational control of the activity. Although variable plasma and liver levels of urate were detected, the substrate increased only slightly in 36% BPM-fed fish, indicating that the uricolytic pathway of Atlantic salmon is intimately regulated to handle high dietary purine levels." @default.
• W1544355286 created "2016-06-24" @default.
• W1544355286 creator A5020300402 @default.
• W1544355286 creator A5030956640 @default.
• W1544355286 creator A5032931583 @default.
• W1544355286 creator A5045358100 @default.
• W1544355286 creator A5069982235 @default.
• W1544355286 creator A5070195975 @default.
• W1544355286 creator A5073667960 @default.
• W1544355286 creator A5091626587 @default.
• W1544355286 date "2006-07-01" @default.
• W1544355286 modified "2023-10-12" @default.
• W1544355286 title "Purine-induced expression of urate oxidase and enzyme activity in Atlantic salmon (Salmo salar)." @default.
• W1544355286 cites W1543266659 @default.
• W1544355286 cites W1580441434 @default.
• W1544355286 cites W1684141345 @default.
• W1544355286 cites W186353762 @default.
• W1544355286 cites W1965743889 @default.
• W1544355286 cites W1968120748 @default.
• W1544355286 cites W1971977264 @default.
• W1544355286 cites W1973607965 @default.
• W1544355286 cites W1975474076 @default.
• W1544355286 cites W1978179663 @default.
• W1544355286 cites W1979192889 @default.
• W1544355286 cites W1981395921 @default.
• W1544355286 cites W1988650861 @default.
• W1544355286 cites W1990680621 @default.
• W1544355286 cites W1996223478 @default.
• W1544355286 cites W1997192616 @default.
• W1544355286 cites W2002116300 @default.
• W1544355286 cites W2002918551 @default.
• W1544355286 cites W2005527892 @default.
• W1544355286 cites W2005603374 @default.
• W1544355286 cites W2006258979 @default.
• W1544355286 cites W2006265318 @default.
• W1544355286 cites W2007709580 @default.
• W1544355286 cites W2007870738 @default.
• W1544355286 cites W2008481607 @default.
• W1544355286 cites W2010834423 @default.
• W1544355286 cites W2012019710 @default.
• W1544355286 cites W2018552952 @default.
• W1544355286 cites W2018749514 @default.
• W1544355286 cites W2019412455 @default.
• W1544355286 cites W2019432189 @default.
• W1544355286 cites W2023153124 @default.
• W1544355286 cites W2025372788 @default.
• W1544355286 cites W2025914558 @default.
• W1544355286 cites W2030152640 @default.
• W1544355286 cites W2050276612 @default.
• W1544355286 cites W2052952311 @default.
• W1544355286 cites W2058322920 @default.
• W1544355286 cites W2063263240 @default.
• W1544355286 cites W2064835823 @default.
• W1544355286 cites W2066162425 @default.
• W1544355286 cites W2081393332 @default.
• W1544355286 cites W2083673199 @default.
• W1544355286 cites W2090044744 @default.
• W1544355286 cites W2091136653 @default.
• W1544355286 cites W2092371038 @default.
• W1544355286 cites W2097090704 @default.
• W1544355286 cites W2099249565 @default.
• W1544355286 cites W2108388593 @default.
• W1544355286 cites W2112322678 @default.
• W1544355286 cites W2128635872 @default.
• W1544355286 cites W2135021302 @default.
• W1544355286 cites W2137260316 @default.
• W1544355286 cites W2138983501 @default.
• W1544355286 cites W2139729474 @default.
• W1544355286 cites W2141275034 @default.
• W1544355286 cites W2142655284 @default.
• W1544355286 cites W2150297520 @default.
• W1544355286 cites W2169266827 @default.
• W1544355286 cites W2170566884 @default.
• W1544355286 cites W2340272663 @default.
• W1544355286 cites W2413610648 @default.
• W1544355286 cites W356299883 @default.
• W1544355286 cites W4236236547 @default.
• W1544355286 cites W4254880152 @default.
• W1544355286 cites W63846950 @default.
• W1544355286 cites W68201349 @default.
• W1544355286 doi "https://doi.org/10.1111/j.1742-4658.2006.05288.x" @default.
• W1544355286 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16759232" @default.
• W1544355286 hasPublicationYear "2006" @default.
• W1544355286 type Work @default.
• W1544355286 sameAs 1544355286 @default.
• W1544355286 citedByCount "38" @default.
• W1544355286 countsByYear W15443552862012 @default.
• W1544355286 countsByYear W15443552862013 @default.
• W1544355286 countsByYear W15443552862015 @default.
• W1544355286 countsByYear W15443552862016 @default.
• W1544355286 countsByYear W15443552862017 @default.
• W1544355286 countsByYear W15443552862019 @default.
• W1544355286 countsByYear W15443552862020 @default.
• W1544355286 countsByYear W15443552862022 @default.
• W1544355286 countsByYear W15443552862023 @default.
• W1544355286 crossrefType "journal-article" @default.
• W1544355286 hasAuthorship W1544355286A5020300402 @default.
• W1544355286 hasAuthorship W1544355286A5030956640 @default.

• next