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- W1545163627 abstract "Cleft lip and palate is the most common craniofacial birth defect and its etiology has been the focus of many reports in the literature. It is well accepted that both genetics and environment play a role in the condition, however we still have not been able to translate what have been learned into clinical applications. This paper provides an interpretation of the latest research findings in humans and a perspective for where the field is going. The latest effort in gene identification and the associations between isolated cleft lip and palate and the loci harboring IRF6 (1q32) and 8q24.21 are highlighted, as well as the latest insight from more sophisticated phenotypical characterization and the inclusion of covariables related to the environment in the analysis of genetic variation." @default.
- W1545163627 created "2016-06-24" @default.
- W1545163627 creator A5023667688 @default.
- W1545163627 date "2012-01-01" @default.
- W1545163627 modified "2023-10-18" @default.
- W1545163627 title "Genetic and Environmental Factors in Human Cleft Lip and Palate" @default.
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- W1545163627 doi "https://doi.org/10.1159/000337521" @default.
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