FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1545473119> ?p ?o ?g. }

• W1545473119 abstract "Ultrasound imaging has been utilized for the non-invasive and real-time observation of pathophysiological conditions in clinical settings. To enhance blood flow signals, microbubbles that are quite different in acoustic impedance from blood have been utilized as the contrast agent for ultrasound imaging. Unfortunately, the initial performance of intravenous contrast-enhanced ultrasound imaging was hampered by the pulmonary circulation due to the size of the microbubbles. Additionally, the detection of microbubbles was not easy because of the weak signals derived from the bubbles. However, recent improvements in the bubble physics and ultrasound imaging technologies have enabled non-invasive assessment of organ perfusion by intravenous administration of microbubbles (Chahal & Senior, 2010; Porter & Xie, 2010; Wilson & Burns, 2010). Of note, the fate of intravenously administrated microbubbles is similar to that of red blood cells (Keller et al., 1989; Jayaweera et al., 1994). Many contrast agents for contrast-enhanced ultrasound imaging are now clinically available all over the world (Table 1). On the other hand, ultrasound molecular imaging, which visualizes molecular dynamics in situ by detecting the signals derived from retained microbubbles in the target regions, has been recently developed. As microbubbles are the intravascular blood flow tracer, ultrasound molecular imaging predominantly targets activated leukocytes and molecules expressed on endothelial cells. Many papers have been published regarding the diagnostic utility of ultrasound molecular imaging for the detection of inflammation, atherosclerosis and tumor angiogenesis (Villanueva & Wagner, 2008; Leong-Poi, 2009; Lindner, 2009; Chadderdon & Kaul, 2010; Deshpande et al., 2010). The utility of molecular imaging has been demonstrated using several modalities, including positron emission tomography (PET), magnetic resonance imaging (MRI) and near-infrared fluorescence (NIRF) (Jaffer & Weissleder, 2005). Although PET and MRI provide accurate diagnostic information, the versatility of these two modalities is limited. On the other hand, ultrasound examination is cost effective and is able to be performed at the bedside. Therefore, the adaptation of ultrasound molecular imaging for clinical settings is desired. For the clinical translation of ultrasound molecular imaging, however, some bottlenecks need to be overcome at the same time, including the development of clinically translatable targeted bubbles and the improvement of ultrasound imaging techniques. This chapter summarizes the recent advances in the preparation of targeted bubbles and ultrasound" @default.
• W1545473119 created "2016-06-24" @default.
• W1545473119 creator A5056890968 @default.
• W1545473119 date "2011-08-23" @default.
• W1545473119 modified "2023-09-23" @default.
• W1545473119 title "Feasibility of Clinical Application of Ultrasound Molecular Imaging" @default.
• W1545473119 cites W1501982791 @default.
• W1545473119 cites W1512026049 @default.
• W1545473119 cites W1546142982 @default.
• W1545473119 cites W1964276203 @default.
• W1545473119 cites W1967271515 @default.
• W1545473119 cites W1969492846 @default.
• W1545473119 cites W1972123675 @default.
• W1545473119 cites W1975085140 @default.
• W1545473119 cites W1978588384 @default.
• W1545473119 cites W1982574363 @default.
• W1545473119 cites W1995472945 @default.
• W1545473119 cites W1999553818 @default.
• W1545473119 cites W2001705635 @default.
• W1545473119 cites W2004595037 @default.
• W1545473119 cites W2004977295 @default.
• W1545473119 cites W2007889229 @default.
• W1545473119 cites W2015047225 @default.
• W1545473119 cites W2021510086 @default.
• W1545473119 cites W2024697030 @default.
• W1545473119 cites W2027489935 @default.
• W1545473119 cites W2027493983 @default.
• W1545473119 cites W2033269131 @default.
• W1545473119 cites W2033380666 @default.
• W1545473119 cites W2034187117 @default.
• W1545473119 cites W2035808299 @default.
• W1545473119 cites W2036329960 @default.
• W1545473119 cites W2036898521 @default.
• W1545473119 cites W2037550744 @default.
• W1545473119 cites W2039317622 @default.
• W1545473119 cites W2040430768 @default.
• W1545473119 cites W2040898123 @default.
• W1545473119 cites W2044399236 @default.
• W1545473119 cites W2046953649 @default.
• W1545473119 cites W2047187470 @default.
• W1545473119 cites W2047628239 @default.
• W1545473119 cites W2057075891 @default.
• W1545473119 cites W2057299289 @default.
• W1545473119 cites W2062437832 @default.
• W1545473119 cites W2063147098 @default.
• W1545473119 cites W2066007175 @default.
• W1545473119 cites W2068364908 @default.
• W1545473119 cites W2071666577 @default.
• W1545473119 cites W2071700707 @default.
• W1545473119 cites W2075048068 @default.
• W1545473119 cites W2078532650 @default.
• W1545473119 cites W2079929192 @default.
• W1545473119 cites W2088946747 @default.
• W1545473119 cites W2089089322 @default.
• W1545473119 cites W2091453134 @default.
• W1545473119 cites W2095379192 @default.
• W1545473119 cites W2097776146 @default.
• W1545473119 cites W2100303262 @default.
• W1545473119 cites W2104657690 @default.
• W1545473119 cites W2106463752 @default.
• W1545473119 cites W2108030846 @default.
• W1545473119 cites W2112923636 @default.
• W1545473119 cites W2120344766 @default.
• W1545473119 cites W2125542444 @default.
• W1545473119 cites W2139080209 @default.
• W1545473119 cites W2144870723 @default.
• W1545473119 cites W2145375426 @default.
• W1545473119 cites W2153671281 @default.
• W1545473119 cites W2158152862 @default.
• W1545473119 cites W2158409077 @default.
• W1545473119 cites W2159527439 @default.
• W1545473119 cites W2159653257 @default.
• W1545473119 cites W2161549257 @default.
• W1545473119 cites W2169346247 @default.
• W1545473119 cites W2169509169 @default.
• W1545473119 cites W2198426489 @default.
• W1545473119 cites W2321506715 @default.
• W1545473119 cites W3147827764 @default.
• W1545473119 doi "https://doi.org/10.5772/17873" @default.
• W1545473119 hasPublicationYear "2011" @default.
• W1545473119 type Work @default.
• W1545473119 sameAs 1545473119 @default.
• W1545473119 citedByCount "1" @default.
• W1545473119 countsByYear W15454731192013 @default.
• W1545473119 crossrefType "book-chapter" @default.
• W1545473119 hasAuthorship W1545473119A5056890968 @default.
• W1545473119 hasBestOaLocation W15454731191 @default.
• W1545473119 hasConcept C126838900 @default.
• W1545473119 hasConcept C136339569 @default.
• W1545473119 hasConcept C143753070 @default.
• W1545473119 hasConcept C150903083 @default.
• W1545473119 hasConcept C19527891 @default.
• W1545473119 hasConcept C207001950 @default.
• W1545473119 hasConcept C2986892559 @default.
• W1545473119 hasConcept C41008148 @default.
• W1545473119 hasConcept C71924100 @default.
• W1545473119 hasConcept C86803240 @default.
• W1545473119 hasConceptScore W1545473119C126838900 @default.
• W1545473119 hasConceptScore W1545473119C136339569 @default.
• W1545473119 hasConceptScore W1545473119C143753070 @default.

• next