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- W1545734517 abstract "The state of chromatin during the cell cycle was examined using synchronized cultures of CHO hamster cells. Results support Mazia's dynamic chromosome cycle model and indicate that DNA-interactive chemotherapeutic agents elicit different types of kinetic responses in treated cells, suggesting a degree of specificity of interaction between various alkylating and intercalating agents and the genome. Effects of sarkosyl crystals, heparin, and chemotherapeutic agents, neocarzinostatin and adriamycin, on chromation are discussed. (HLW)" @default.
- W1545734517 created "2016-06-24" @default.
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- W1545734517 date "1976-01-01" @default.
- W1545734517 modified "2023-09-27" @default.
- W1545734517 title "Cell-cycle-related biosynthesis. [Sarkosyl, neocarzinostatin, adriamycin]" @default.
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