Matches in SemOpenAlex for { <https://semopenalex.org/work/W1546095110> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W1546095110 endingPage "587" @default.
- W1546095110 startingPage "577" @default.
- W1546095110 abstract "The stabilities of three different RNA fragments have been measured as a function of Mg2+ concentrations, and are interpreted in terms of two different models of Mg2+-RNA interaction. The models presume either tight binding of ions to specific site(s) in a folded RNA, or non-specific, electrostatic binding to both folded and unfolded forms; qualitatively different predictions are made for the melting temperature dependence on ion concentration. Three different modes of Mg2+ interactions with RNA structures are distinguished. Hairpins are stabilized by completely non-specific binding, with affinities the same as or weaker than those for single strand and duplex homopolymers binding Mg2+. In contrast, a ribosomal RNA tertiary structure is stabilized by specific binding of a single ion; since no other di- or trivalent ion is as effective as Mg2+, direct coordination of Mg2+ to the RNA structure is probably taking place. A third class of sites is best analyzed by the site-specific model, but any di- or trivalent ion is as effective as Mg2+; the ion(s) are probably localized in a region of unusually high charge density. The magnitude of a Mg2+ -induced shift in RNA tm is itself not diagnostic of specific site binding or RNA tertiary structure, since large shifts can be observed for all three interaction modes." @default.
- W1546095110 created "2016-06-24" @default.
- W1546095110 creator A5043889077 @default.
- W1546095110 creator A5064334498 @default.
- W1546095110 creator A5070137271 @default.
- W1546095110 date "1994-04-01" @default.
- W1546095110 modified "2023-10-16" @default.
- W1546095110 title "Stabilization of RNA Structure by Mg Ions" @default.
- W1546095110 doi "https://doi.org/10.1006/jmbi.1994.1256" @default.
- W1546095110 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8158638" @default.
- W1546095110 hasPublicationYear "1994" @default.
- W1546095110 type Work @default.
- W1546095110 sameAs 1546095110 @default.
- W1546095110 citedByCount "146" @default.
- W1546095110 countsByYear W15460951102013 @default.
- W1546095110 countsByYear W15460951102014 @default.
- W1546095110 countsByYear W15460951102015 @default.
- W1546095110 countsByYear W15460951102016 @default.
- W1546095110 countsByYear W15460951102019 @default.
- W1546095110 countsByYear W15460951102020 @default.
- W1546095110 countsByYear W15460951102021 @default.
- W1546095110 countsByYear W15460951102022 @default.
- W1546095110 countsByYear W15460951102023 @default.
- W1546095110 crossrefType "journal-article" @default.
- W1546095110 hasAuthorship W1546095110A5043889077 @default.
- W1546095110 hasAuthorship W1546095110A5064334498 @default.
- W1546095110 hasAuthorship W1546095110A5070137271 @default.
- W1546095110 hasBestOaLocation W15460951101 @default.
- W1546095110 hasConcept C104317684 @default.
- W1546095110 hasConcept C107824862 @default.
- W1546095110 hasConcept C12554922 @default.
- W1546095110 hasConcept C126142528 @default.
- W1546095110 hasConcept C145148216 @default.
- W1546095110 hasConcept C159467904 @default.
- W1546095110 hasConcept C178790620 @default.
- W1546095110 hasConcept C185592680 @default.
- W1546095110 hasConcept C2780283098 @default.
- W1546095110 hasConcept C552990157 @default.
- W1546095110 hasConcept C55493867 @default.
- W1546095110 hasConcept C67705224 @default.
- W1546095110 hasConcept C71240020 @default.
- W1546095110 hasConcept C75599170 @default.
- W1546095110 hasConcept C8010536 @default.
- W1546095110 hasConcept C86803240 @default.
- W1546095110 hasConcept C99611785 @default.
- W1546095110 hasConceptScore W1546095110C104317684 @default.
- W1546095110 hasConceptScore W1546095110C107824862 @default.
- W1546095110 hasConceptScore W1546095110C12554922 @default.
- W1546095110 hasConceptScore W1546095110C126142528 @default.
- W1546095110 hasConceptScore W1546095110C145148216 @default.
- W1546095110 hasConceptScore W1546095110C159467904 @default.
- W1546095110 hasConceptScore W1546095110C178790620 @default.
- W1546095110 hasConceptScore W1546095110C185592680 @default.
- W1546095110 hasConceptScore W1546095110C2780283098 @default.
- W1546095110 hasConceptScore W1546095110C552990157 @default.
- W1546095110 hasConceptScore W1546095110C55493867 @default.
- W1546095110 hasConceptScore W1546095110C67705224 @default.
- W1546095110 hasConceptScore W1546095110C71240020 @default.
- W1546095110 hasConceptScore W1546095110C75599170 @default.
- W1546095110 hasConceptScore W1546095110C8010536 @default.
- W1546095110 hasConceptScore W1546095110C86803240 @default.
- W1546095110 hasConceptScore W1546095110C99611785 @default.
- W1546095110 hasIssue "5" @default.
- W1546095110 hasLocation W15460951101 @default.
- W1546095110 hasLocation W15460951102 @default.
- W1546095110 hasOpenAccess W1546095110 @default.
- W1546095110 hasPrimaryLocation W15460951101 @default.
- W1546095110 hasRelatedWork W1472344963 @default.
- W1546095110 hasRelatedWork W1546095110 @default.
- W1546095110 hasRelatedWork W2042994656 @default.
- W1546095110 hasRelatedWork W2058276221 @default.
- W1546095110 hasRelatedWork W2075924119 @default.
- W1546095110 hasRelatedWork W2089828997 @default.
- W1546095110 hasRelatedWork W2097627156 @default.
- W1546095110 hasRelatedWork W2470187006 @default.
- W1546095110 hasRelatedWork W4237472082 @default.
- W1546095110 hasRelatedWork W4238806314 @default.
- W1546095110 hasVolume "237" @default.
- W1546095110 isParatext "false" @default.
- W1546095110 isRetracted "false" @default.
- W1546095110 magId "1546095110" @default.
- W1546095110 workType "article" @default.