Matches in SemOpenAlex for { <https://semopenalex.org/work/W1546474208> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W1546474208 abstract "Abstract : Atropine dosing ranging from 0.5 to 4.0 mg demonstrated significant cognitive-neuromotor impairment effects in the 2.0 and 4.0 mg dose. The effects shown after the 4.0 mg dose was of a much greater magnitude and duration than that of the 2.0 mg dose. However, all dose of atropine induced significant tachycardia which declined much more rapidly than performance measures. The pharmacokinetics of I.M. atropine can be best described by a two-compartment with very fast first order adsorption. For all doses, atropine plasma levels and heart rate changes closely overlapped throughout the time course. In contrast, the differential time course of changes in atropine levels and behavioral impairment indicates that pharmacokinetics is not the primary rate limiting mechanism for brain effects of atropine. Potential differences in time course effects on M1 vs M2 receptors raise the question of whether some of the protective effects of atropine may not be maintained as long as other effects." @default.
- W1546474208 created "2016-06-24" @default.
- W1546474208 creator A5017705797 @default.
- W1546474208 creator A5025763710 @default.
- W1546474208 creator A5040361069 @default.
- W1546474208 creator A5047646942 @default.
- W1546474208 creator A5058027314 @default.
- W1546474208 date "1988-09-01" @default.
- W1546474208 modified "2023-09-22" @default.
- W1546474208 title "Effects of Cholinergic Perturbations on Neuromotor - Cognitive Performance" @default.
- W1546474208 hasPublicationYear "1988" @default.
- W1546474208 type Work @default.
- W1546474208 sameAs 1546474208 @default.
- W1546474208 citedByCount "0" @default.
- W1546474208 crossrefType "journal-article" @default.
- W1546474208 hasAuthorship W1546474208A5017705797 @default.
- W1546474208 hasAuthorship W1546474208A5025763710 @default.
- W1546474208 hasAuthorship W1546474208A5040361069 @default.
- W1546474208 hasAuthorship W1546474208A5047646942 @default.
- W1546474208 hasAuthorship W1546474208A5058027314 @default.
- W1546474208 hasConcept C112705442 @default.
- W1546474208 hasConcept C126322002 @default.
- W1546474208 hasConcept C127413603 @default.
- W1546474208 hasConcept C15744967 @default.
- W1546474208 hasConcept C170493617 @default.
- W1546474208 hasConcept C188198153 @default.
- W1546474208 hasConcept C22885893 @default.
- W1546474208 hasConcept C2775859210 @default.
- W1546474208 hasConcept C2776291473 @default.
- W1546474208 hasConcept C2777288759 @default.
- W1546474208 hasConcept C2777953023 @default.
- W1546474208 hasConcept C2778689640 @default.
- W1546474208 hasConcept C2780283014 @default.
- W1546474208 hasConcept C33789571 @default.
- W1546474208 hasConcept C42219234 @default.
- W1546474208 hasConcept C71924100 @default.
- W1546474208 hasConcept C78519656 @default.
- W1546474208 hasConcept C84393581 @default.
- W1546474208 hasConceptScore W1546474208C112705442 @default.
- W1546474208 hasConceptScore W1546474208C126322002 @default.
- W1546474208 hasConceptScore W1546474208C127413603 @default.
- W1546474208 hasConceptScore W1546474208C15744967 @default.
- W1546474208 hasConceptScore W1546474208C170493617 @default.
- W1546474208 hasConceptScore W1546474208C188198153 @default.
- W1546474208 hasConceptScore W1546474208C22885893 @default.
- W1546474208 hasConceptScore W1546474208C2775859210 @default.
- W1546474208 hasConceptScore W1546474208C2776291473 @default.
- W1546474208 hasConceptScore W1546474208C2777288759 @default.
- W1546474208 hasConceptScore W1546474208C2777953023 @default.
- W1546474208 hasConceptScore W1546474208C2778689640 @default.
- W1546474208 hasConceptScore W1546474208C2780283014 @default.
- W1546474208 hasConceptScore W1546474208C33789571 @default.
- W1546474208 hasConceptScore W1546474208C42219234 @default.
- W1546474208 hasConceptScore W1546474208C71924100 @default.
- W1546474208 hasConceptScore W1546474208C78519656 @default.
- W1546474208 hasConceptScore W1546474208C84393581 @default.
- W1546474208 hasLocation W15464742081 @default.
- W1546474208 hasOpenAccess W1546474208 @default.
- W1546474208 hasPrimaryLocation W15464742081 @default.
- W1546474208 hasRelatedWork W1608294617 @default.
- W1546474208 hasRelatedWork W1854031644 @default.
- W1546474208 hasRelatedWork W1996843128 @default.
- W1546474208 hasRelatedWork W2021970298 @default.
- W1546474208 hasRelatedWork W2022014120 @default.
- W1546474208 hasRelatedWork W2023867224 @default.
- W1546474208 hasRelatedWork W2028475609 @default.
- W1546474208 hasRelatedWork W2040091789 @default.
- W1546474208 hasRelatedWork W2050636393 @default.
- W1546474208 hasRelatedWork W2086830572 @default.
- W1546474208 hasRelatedWork W2116237116 @default.
- W1546474208 hasRelatedWork W2156810371 @default.
- W1546474208 hasRelatedWork W2189378484 @default.
- W1546474208 hasRelatedWork W2325233819 @default.
- W1546474208 hasRelatedWork W2330603776 @default.
- W1546474208 hasRelatedWork W2444430061 @default.
- W1546474208 hasRelatedWork W2515570416 @default.
- W1546474208 hasRelatedWork W2599981879 @default.
- W1546474208 hasRelatedWork W3212803434 @default.
- W1546474208 hasRelatedWork W3082480518 @default.
- W1546474208 isParatext "false" @default.
- W1546474208 isRetracted "false" @default.
- W1546474208 magId "1546474208" @default.
- W1546474208 workType "article" @default.