Matches in SemOpenAlex for { <https://semopenalex.org/work/W1547642004> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W1547642004 endingPage "637" @default.
- W1547642004 startingPage "631" @default.
- W1547642004 abstract "A method for the selective detection of creatinine is reported, which is based on the reaction between polymerised hemithioacetal, formed by allyl mercaptan, o-phthalic aldehyde, and primary amine leading to the formation of fluorescent isoindole complex. This method has been demonstrated previously for the detection of creatine using creatine-imprinted molecularly imprinted polymers (MIPs) Since MIPs created using traditional methods were unable to differentiate between creatine and creatinine, a new approach to the rational design of a molecularly imprinted polymer (MIP) selective for creatinine was developed using computer simulation. A virtual library of functional monomers was assigned and screened against the target molecule, creatinine, using molecular modelling software. The monomers giving the highest binding score were further tested using simulated annealing in order to mimic the complexation of the functional monomers with template in the monomer mixture. The result of this simulation gave an optimised MIP composition. The computationally designed polymer demonstrated superior selectivity in comparison to the polymer prepared using traditional approach, a detection limit of 25 microM and good stability. The Bite-and-Switch approach combined with molecular imprinting can be used for the design of assays and sensors, selective for amino containing substances." @default.
- W1547642004 created "2016-06-24" @default.
- W1547642004 creator A5001362474 @default.
- W1547642004 creator A5020099630 @default.
- W1547642004 creator A5032419101 @default.
- W1547642004 creator A5060720531 @default.
- W1547642004 creator A5070676945 @default.
- W1547642004 creator A5072010816 @default.
- W1547642004 date "2001-12-01" @default.
- W1547642004 modified "2023-10-17" @default.
- W1547642004 title "‘Bite-and-Switch’ approach using computationally designed molecularly imprinted polymers for sensing of creatinine11Editors Selection" @default.
- W1547642004 cites W1985584940 @default.
- W1547642004 cites W1998702649 @default.
- W1547642004 cites W2005996235 @default.
- W1547642004 cites W2007203981 @default.
- W1547642004 cites W2012996079 @default.
- W1547642004 cites W2014256613 @default.
- W1547642004 cites W2027328560 @default.
- W1547642004 cites W2057742324 @default.
- W1547642004 cites W2061551326 @default.
- W1547642004 cites W2078026920 @default.
- W1547642004 cites W2079633116 @default.
- W1547642004 cites W2085790519 @default.
- W1547642004 cites W2093667279 @default.
- W1547642004 cites W2103352542 @default.
- W1547642004 cites W2148845788 @default.
- W1547642004 cites W4254870942 @default.
- W1547642004 doi "https://doi.org/10.1016/s0956-5663(01)00191-9" @default.
- W1547642004 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11679238" @default.
- W1547642004 hasPublicationYear "2001" @default.
- W1547642004 type Work @default.
- W1547642004 sameAs 1547642004 @default.
- W1547642004 citedByCount "171" @default.
- W1547642004 countsByYear W15476420042012 @default.
- W1547642004 countsByYear W15476420042013 @default.
- W1547642004 countsByYear W15476420042014 @default.
- W1547642004 countsByYear W15476420042015 @default.
- W1547642004 countsByYear W15476420042016 @default.
- W1547642004 countsByYear W15476420042017 @default.
- W1547642004 countsByYear W15476420042018 @default.
- W1547642004 countsByYear W15476420042019 @default.
- W1547642004 countsByYear W15476420042020 @default.
- W1547642004 countsByYear W15476420042021 @default.
- W1547642004 countsByYear W15476420042022 @default.
- W1547642004 countsByYear W15476420042023 @default.
- W1547642004 crossrefType "journal-article" @default.
- W1547642004 hasAuthorship W1547642004A5001362474 @default.
- W1547642004 hasAuthorship W1547642004A5020099630 @default.
- W1547642004 hasAuthorship W1547642004A5032419101 @default.
- W1547642004 hasAuthorship W1547642004A5060720531 @default.
- W1547642004 hasAuthorship W1547642004A5070676945 @default.
- W1547642004 hasAuthorship W1547642004A5072010816 @default.
- W1547642004 hasConcept C118792377 @default.
- W1547642004 hasConcept C119128265 @default.
- W1547642004 hasConcept C161790260 @default.
- W1547642004 hasConcept C162602672 @default.
- W1547642004 hasConcept C166940927 @default.
- W1547642004 hasConcept C178790620 @default.
- W1547642004 hasConcept C185592680 @default.
- W1547642004 hasConcept C21951064 @default.
- W1547642004 hasConcept C39442485 @default.
- W1547642004 hasConcept C43617362 @default.
- W1547642004 hasConcept C521977710 @default.
- W1547642004 hasConceptScore W1547642004C118792377 @default.
- W1547642004 hasConceptScore W1547642004C119128265 @default.
- W1547642004 hasConceptScore W1547642004C161790260 @default.
- W1547642004 hasConceptScore W1547642004C162602672 @default.
- W1547642004 hasConceptScore W1547642004C166940927 @default.
- W1547642004 hasConceptScore W1547642004C178790620 @default.
- W1547642004 hasConceptScore W1547642004C185592680 @default.
- W1547642004 hasConceptScore W1547642004C21951064 @default.
- W1547642004 hasConceptScore W1547642004C39442485 @default.
- W1547642004 hasConceptScore W1547642004C43617362 @default.
- W1547642004 hasConceptScore W1547642004C521977710 @default.
- W1547642004 hasIssue "9-12" @default.
- W1547642004 hasLocation W15476420041 @default.
- W1547642004 hasLocation W15476420042 @default.
- W1547642004 hasOpenAccess W1547642004 @default.
- W1547642004 hasPrimaryLocation W15476420041 @default.
- W1547642004 hasRelatedWork W1481553916 @default.
- W1547642004 hasRelatedWork W2009539482 @default.
- W1547642004 hasRelatedWork W2078058573 @default.
- W1547642004 hasRelatedWork W2123923310 @default.
- W1547642004 hasRelatedWork W2341353322 @default.
- W1547642004 hasRelatedWork W2360824019 @default.
- W1547642004 hasRelatedWork W2385413370 @default.
- W1547642004 hasRelatedWork W2387985903 @default.
- W1547642004 hasRelatedWork W4307942417 @default.
- W1547642004 hasRelatedWork W4386824314 @default.
- W1547642004 hasVolume "16" @default.
- W1547642004 isParatext "false" @default.
- W1547642004 isRetracted "false" @default.
- W1547642004 magId "1547642004" @default.
- W1547642004 workType "article" @default.