FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1547648210> ?p ?o ?g. }

• W1547648210 endingPage "169" @default.
• W1547648210 startingPage "149" @default.
• W1547648210 abstract "The mechanisms and outcome of cerebral ischemic injury are influenced strongly by biological sex and the availability of female and male sex steroids to the brain. This chapter evaluates the data suggesting that biological sex determines clinical and experimental stroke outcomes, reviews special considerations for women with stroke, summarizes the controversy behind estrogen's antiischemic and neuroprotective properties, andintroduces the novel idea that androgens contribute to ischemic sensitivity in the male brain. The epidemiology of ischemic stroke is sexually dimorphic in that ischemic events occur with greater frequency in men than in women regardless of country of origin and ethnic culture. The potential for sex-specific responses to treatments or the possibility that endogenous or exogenous sex steroids may interact with treatments is observed. The pleiotropic estrogens are linked to the early protection from stroke in women. The mechanism attenuating the beneficial effects of estrogen is loss of arterial estrogen receptors. Loss of the estrogen receptors occurs with aging and is more prominent in atherosclerotic vessels. Male sex is an acknowledged risk factor for human stroke. Testosterone acts as a type of prohormone with two distinct conversion pathways. In all androgen-sensitive tissues, the steroid is converted intracellularly to either the more potent androgen dihydrotestosterone or to E2. It is hypothesized that androgens enhance ischemic damage and may play a role in male stroke." @default.
• W1547648210 created "2016-06-24" @default.
• W1547648210 creator A5005438739 @default.
• W1547648210 creator A5015699563 @default.
• W1547648210 creator A5035455397 @default.
• W1547648210 date "2008-01-01" @default.
• W1547648210 modified "2023-09-23" @default.
• W1547648210 title "Chapter 8 Effects of gender and sex steroids on ischemic injury" @default.
• W1547648210 cites W1483832212 @default.
• W1547648210 cites W1506768719 @default.
• W1547648210 cites W1509103176 @default.
• W1547648210 cites W1529384397 @default.
• W1547648210 cites W1538903611 @default.
• W1547648210 cites W1543006644 @default.
• W1547648210 cites W1563459863 @default.
• W1547648210 cites W1582815982 @default.
• W1547648210 cites W1586699954 @default.
• W1547648210 cites W1593442063 @default.
• W1547648210 cites W1647805770 @default.
• W1547648210 cites W171118067 @default.
• W1547648210 cites W1740376762 @default.
• W1547648210 cites W1771495220 @default.
• W1547648210 cites W1809411463 @default.
• W1547648210 cites W1862183284 @default.
• W1547648210 cites W1918726675 @default.
• W1547648210 cites W1928820616 @default.
• W1547648210 cites W1930502921 @default.
• W1547648210 cites W1936464499 @default.
• W1547648210 cites W1954362983 @default.
• W1547648210 cites W1954468845 @default.
• W1547648210 cites W1956013732 @default.
• W1547648210 cites W1962264436 @default.
• W1547648210 cites W1963092557 @default.
• W1547648210 cites W1965582720 @default.
• W1547648210 cites W1966701899 @default.
• W1547648210 cites W1968981889 @default.
• W1547648210 cites W1968998907 @default.
• W1547648210 cites W1969495118 @default.
• W1547648210 cites W1972368286 @default.
• W1547648210 cites W1973051454 @default.
• W1547648210 cites W1974730873 @default.
• W1547648210 cites W1977463652 @default.
• W1547648210 cites W1979721685 @default.
• W1547648210 cites W1980535385 @default.
• W1547648210 cites W1980883418 @default.
• W1547648210 cites W1981277980 @default.
• W1547648210 cites W1983352946 @default.
• W1547648210 cites W1985002988 @default.
• W1547648210 cites W1986186900 @default.
• W1547648210 cites W1986963388 @default.
• W1547648210 cites W1986975209 @default.
• W1547648210 cites W1988122391 @default.
• W1547648210 cites W1988369035 @default.
• W1547648210 cites W1991158043 @default.
• W1547648210 cites W1991307433 @default.
• W1547648210 cites W1992983370 @default.
• W1547648210 cites W1997570118 @default.
• W1547648210 cites W1998025239 @default.
• W1547648210 cites W1998083451 @default.
• W1547648210 cites W1998136856 @default.
• W1547648210 cites W2000410035 @default.
• W1547648210 cites W2000638100 @default.
• W1547648210 cites W2001680513 @default.
• W1547648210 cites W2002540073 @default.
• W1547648210 cites W2003515483 @default.
• W1547648210 cites W2004451449 @default.
• W1547648210 cites W2004697801 @default.
• W1547648210 cites W2007980908 @default.
• W1547648210 cites W2008075970 @default.
• W1547648210 cites W2010409400 @default.
• W1547648210 cites W2010634774 @default.
• W1547648210 cites W2011566965 @default.
• W1547648210 cites W2013636050 @default.
• W1547648210 cites W2015331364 @default.
• W1547648210 cites W2016818296 @default.
• W1547648210 cites W2019554063 @default.
• W1547648210 cites W2019647253 @default.
• W1547648210 cites W2025039880 @default.
• W1547648210 cites W2025641775 @default.
• W1547648210 cites W2025716332 @default.
• W1547648210 cites W2025968707 @default.
• W1547648210 cites W2027014741 @default.
• W1547648210 cites W2027061276 @default.
• W1547648210 cites W2028504212 @default.
• W1547648210 cites W2030752479 @default.
• W1547648210 cites W2031471554 @default.
• W1547648210 cites W2031710238 @default.
• W1547648210 cites W2032479830 @default.
• W1547648210 cites W2032490010 @default.
• W1547648210 cites W2032562748 @default.
• W1547648210 cites W2034175214 @default.
• W1547648210 cites W2034391942 @default.
• W1547648210 cites W2034993146 @default.
• W1547648210 cites W2035072448 @default.
• W1547648210 cites W2037148314 @default.
• W1547648210 cites W2037849318 @default.
• W1547648210 cites W2040646620 @default.
• W1547648210 cites W2043980476 @default.

• next